Clinical Trial Abstracts

Since the late 1970s there have been many trials and studies carried out on Low Dose Naltrexone, LDN

Below you will find a list of published papers, which we will update as they become available.

Low dose naltrexone in refractory neuropathic pain associated with autoimmune transverse myelitis (Abstract)
Sjogren's Syndrome: Clinical Benefits of Low-dose Naltrexone Therapy (Abstract)
Use of Subcutaneous and Intraperitoneal Administration Methods to Facilitate Cassette Dosing... (Abstract)
Low dose naltrexone therapy in multiple sclerosis (Abstract)
Influence of low dose naltrexone on Raman assisted bone quality, skeletal advanced glycation... (Abstract)
In Response Comments on "Low-Dose Naltrexone Use for Patients with Chronic Regional Pain Syndrome: A Systematic Literature Review" (Abstract)
Reversible Hair Loss in Lichen Planopilaris: Regrowth With Low-Dose Naltrexone and Platelet-Rich Plasma (Abstract)
Low-dose naltrexone in the treatment of fibromyalgia: A systematic review and narrative synthesis (Abstract)
Potential pathophysiological role of the ion channel TRPM3 in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and the therapeutic effect of low-dose naltrexone
Low-dose Naltrexone for the treatment of sarcoidosis (Abstract)
The use of Low-Dose Naltrexone (LDN) as a novel anti-inflammatory treatment for chronic pain (Abstract)
Potentiation of buprenorphine antinociception with ultra-low dose naltrexone in healthy subjects (Abstract)
Low-dose naltrexone effects on plasma chemistries and... (Abstract)
Potential antidepressant role of low-dose naltrexone in a rat model of chronic unpredictable mild stress (Abstract)
Press Release: WAYT-less™ by Nu Image Medical® Exceeds All Projections for Q4 2020
Low-dose Naltrexone: An Alternative Treatment for Erythrodermic Psoriasis (Abstract)
Morphine reduced perceived anger from neutral and implicit emotional expressions (Abstract)
Low-dose naltrexone therapy improves active Crohn's disease (Abstract)
Efficacy and safety of low-dose naltrexone in painful diabetic neuropathy: ... (Abstract)
Effect of Low-Dose Naltrexone on Egyptian Children with Intractable Epilepsy: A Case Series Study (Abstract)
The role of immune modulation and anti-inflammatory agents in the management of prostate cancer... (Abstract)
Acute Low Dose Naltrexone Increases β-Endorphin and Promotes Neuronal Recovery ... (Abstract)
A Utilization Review of Patients That Respond to Low-Dose Naltrexone (LDN) for Chronic Pain at a Single Institution
Low-Dose Naltrexone Reverses Facial Mechanical Allodynia in a Rat Model of Trigeminal Neuralgia (Abstract)
Low-Dose Naltrexone reduces symptoms in Stiff-Person Syndrome (Abstract)
Naltrexone and communication skills in young children with autism (Abstract)
Efficacy of low dose naltrexone as an immune stabilizing agent for the treatment of HIV/AIDS (Abstract)
Low Dose Naltrexone for Neuropathic Pain Related to an Electrical Burn Injury: A Case Study (Article)
A potential anti-inflammatory effect of low-dose naltrexone in fibromyalgia (Abstract)
Combination of Clinically Utilized Kappa-Opioid Receptor Agonist Nalfurafine With Low-Dose Naltrexone... (Abstract)
The multifaceted role of astrocytes in regulating myelination (Abstract)
Low-dose naltrexone for treatment of duodenal Crohn's disease in a pediatric patient (Abstract)
Pharmacotherapy of obesity: An update (Abstract)
Study protocol ... examining the add-on efficacy, cost-utility of low-dose naltrexone ... in patients with fibromyalgia (Abstract)
Recalcitrant Hailey-Hailey Disease Successfully Treated with Low-dose Naltrexone (Abstract)
Low-Dose Naltrexone (LDN) for Chronic Pain at a Single Institution: A Case Series (Abstract)
Low-dose naltrexone inhibits the epithelial-mesenchymal transition of cervical cancer cells... (Abstract)
Very low dose naltrexone in opioid detoxification: a double-blind, randomized clinical trial of efficacy and safety (Abstract)
Endogenous opioids regulate expression of experimental autoimmune encephalomyelitis... (Abstract)
Acquired immunodeficiency syndrome: molecular biology and its therapeutic intervention (review) (Abstract)
Disease remission after commencing naltrexone in an atypical case of Crohn’s disease... (Abstract)
Low Doses Naltrexone: The Potential Benefit Effects for its Use in Patients with Cancer (Abstract)
Low dose naltrexone: Effects on medication in rheumatoid and seropositive arthritis.,, (Abstract)
Effects of Varenicline Alone and in Combination With Low-dose Naltrexone on Alcohol-primed Smoking... (Abstract)
Low Dose Naltrexone in the Treatment of Crohn's Disease: A Case Series (Abstract)
Low-Dose Naltrexone Use for Patients with Chronic Regional Pain Syndrome... (Abstract)
Human herpesvirus-6 viral load and antibody titer in serum samples of patients with multiple sclerosis (Abstract)
Association of low-dose naltrexone and transcranial direct current stimulation in fibromyalgia... (Abstract)
Ocular surface itch and pain: key differences and similarities between the two sensations (Abstract)
Abstract #13: Low-Dose Naltrexone's Tolerability and Effects in Fatigued Patients with Parkinson's Disease: An Open-Label Study (Abstract)
Outpatient transition to extended-release injectable naltrexone for patients with opioid use disorder: A phase 3 randomized trial (Abstract)
Oxycodone plus ultra-low-dose naltrexone attenuates neuropathic pain and associated mu-opioid receptor-Gs coupling (Abstract)
Low dose naltrexone (LDN) enhances maturation of bone marrow dendritic cells (BMDCs) (Abstract)
Use of low dose naltrexone and change in use of prescription drugs in patients with inflammatory bowel disease... (Abstract)
Dose Escalation of Naltrexone to Reduce Stress Responses Associated With Opioid Antagonist Induction... (Abstract)
Clinical utility of the cold pressor test: evaluation of pain patients... (Abstract)
Co-Administration of Low-Dose Naltrexone and Bupropion Reduces Alcohol Drinking... (Abstract)
Long-term remission of adenoid cystic tongue carcinoma with low dose naltrexone... (Abstract)
Integrated Review of the Assessment of Newborns With Neonatal Abstinence Syndrome (Abstract)
Relationship of human herpes virus 6 and multiple sclerosis: A systematic review and meta-analysis (Abstract)
Ultra-low dose naloxone restores the antinocicepitve effect of morphine in... (Abstract)
Combination therapy: A New Tool for the Management of Obesity (Abstract)
Warning - Fake Medications
Low-Dose Naltrexone Treatment of Familial Benign Pemphigus (Hailey-Hailey Disease) (Abstract)
Low-dose Naltrexone Therapy for Psoriasis (Abstract)
Opiate hypothesis in infantile autism? Therapeutic trials with naltrexone (Abstract)
Opioid-immune interactions in autism... (Abstract)
Low-dose naltrexone and opioid consumption: a drug utilization cohort study... (Abstract)
Microglial Phagocytosis of Neurons: Diminishing Neuronal Loss in Traumatic, Infectious, Inflammatory, and Autoimmune CNS Disorders (Abstract)
Intermittent blockade of OGFr and treatment of autoimmune disorders (Abstract)
Combination therapy for obesity (Abstract)
Low dose naltrexone in therapy resistant IBD, a case series (Abstract)
Low Dose Naltrexone in Endometrial Intraepithelial Neoplasia (Abstract)
The putative role of oxidative stress and inflammation in the pathophysiology of sleep dysfunction ... (Abstract)
A Comprehensive Review: Chronic Pain Sequelae in the Presence of Ehlers-Danlos Syndrome (Abstract)
Low-dose naltrexone use for the management of post-acute sequelae of COVID-19 (Abstract)
Low-Dose Naltrexone: An Inexpensive Medicine for Many Ills? (Abstract)
Recalcitrant Hailey-Hailey Disease Successfully Treated with Low-dose Naltrexone(Abstract)
Low‐dose naltrexone in Hailey–Hailey disease: the importance of dosing (Abstract)
Naltrexone in autistic children: an acute open dose range tolerance trial (Abstract)
Repurposing Medications—Chicken Manure, Erectile Dysfunction, and Finding the Golden Needle in the Haystack of Absurdity (Abstract)
Functional modulation on macrophage by low dose naltrexone (LDN) (Abstract)
Anxiolytics, adrenergic agents, and naltrexone (Abstract)
Utility of Naltrexone Treatment for Chronic Inflammatory Dermatologic Condition... (Abstract)
Low dose naltrexone in multiple sclerosis: Effects on medication use... (Abstract)
Opioid growth factor (OGF) for hepatoblastoma: a novel non-toxic treatment (Abstract)
Immunometabolic Modulatory Role of Naltrexone in BV-2 Microglia Cells (Abstract)
Geo-Statistical Analysis of Possible Spirochetal Involvement in Multiple Sclerosis (Abstract)
Off-label pharmacological treatment for neuropathic pain... (Abstract)
Treatment of dissociative symptoms with opioid antagonists: a systematic review (Abstract)
Use of low-dose naltrexone in the management of chronic pain conditions: A systematic review (Abstract)
Successful induction of ovulation in normogonadotrophic clomiphene resistant anovulatory women... (Abstract)
The efficacy and safety of oral low dose naltrexone versus placebo in the patients with lichen planopilaris... (Abstract)
Prevention and diminished expression of experimental autoimmune encephalomyelitis by low dose naltrexone (LDN) or opioid growth factor (OGF)... (Abstract)
Low-Dose Naltrexone (LDN)-Review of Therapeutic Utilization (Abstract)
Low-Dose Naltrexone: A New Therapy Option for Complex Regional Pain Syndrome Type I Patients (Abstract)
Long-term effects of naltrexone on self-injurious behavior (Abstract)
Treatment of psoriasis vulgaris using low-dose naltrexone (Abstract)
Low-dose naltrexone: a novel treatment for Hailey-Hailey disease (Abstract)
Immunological changes in IBD patients responding to low-dose naltrexone treatment (Abstract)