Complex Regional Pain Syndrome: A Comprehensive Review 

Pain Ther
24 June 2021

Low-Dose Naltrexone Use for Patients with Chronic Regional Pain Syndrome: A Systematic Literature Review

Pain Physician
July 2021

Background: Complex regional pain syndrome is a rare, neuropathic disorder that affects fewer than 200,000 individuals in the United States annually. Current treatments often focus on pain management and fall short of relieving symptoms of pain and dystonia in patients.

Low-Dose Naltrexone May Be Opioid Replacement for Chronic Pain

Verywell Health
04 March 2021

Treatment of Complex Regional Pain Syndrome (CRPS) Using Low Dose Naltrexone (LDN)

J Neuroimmune Pharmacol
June 2013

No Antagonists for an Antagonist: One Pitfall of Chronic Oral Low-Dose Naltrexone

Pain Medicine
December 2015

A 48 year old man with 10 years of chronic abdominal pain following an open repair of an abdominal aortic aneurysm was treated with low dose naltrexone 1.5mg/day for 3 years with satisfactory results.


Low-Dose Naltrexone: A New Therapy Option for Complex Regional Pain Syndrome Type I Patients

Int J Pharm Compd
May-June 2016

Low-Dose Naltrexone (LDN)-Review of Therapeutic Utilization

Medical Sciences
21 September 2018

Identfication and Treatment of New Inflammatory Triggers for Complex Regional Pain Syndrome: Small Intestinal Bacterial Overgrowth and Obstructive Sleep Apnea

A A Case Rep
May 2016

Naltrexone Hydrochloride 1.5-mg and 4.5-mg Capsules

US Pharm
19 March 2020



Sarah Zielsdorf, MD, 2019 Pain Seminar in CT (LDN 2019 Pain Seminar) from LDN Research Trust on Vimeo.

Dr Sarah Zielsdorf shares her presentation on Pain at The LDN 2019 Pain Seminar.