Clinical Trials | LDN Research Trust

The efficacy and safety of oral low dose naltrexone versus placebo in the patients with lichen planopilaris; a randomized controlled clinical trial

Condition: Autoimmune, Lichen, Skin

Erythromelalgia in a Patient with Mast Cell Activation Syndrome: Response to Low Dose Naltrexone

Condition: Pain, Skin

Anticonvulsant Effects of Thalidomide on Pentylenetetrazole-Induced Seizure in Mice: A Role for Opioidergic and Nitrergic Transmissions

Condition: Opiod, Seizure

Effects of Acute and Repeated Treatment With Methocinnamox, a Mu Opioid Receptor Antagonist, on Fentanyl Self-Administration in Rhesus Monkeys

Condition: Opiod, Pain

129 Medication Assisted Treatment Protocol

Condition: Opiod, Pain

Low-dose Naltrexone Therapy for Psoriasis

Condition: Autoimmune, Skin, Psoriasis

Transition of Patients With Opioid Use Disorder From Buprenorphine to Extended-Release Naltrexone: A Randomized Clinical Trial Assessing Two Transition Regimens

Condition: Opiod, Pain

Naltrexone Hydrochloride 1.5-mg and 4.5-mg Capsules

Condition: Complex Regional Pain Syndrome, Fibromyalgia, Pain, Psoriasis

Low-dose naltrexone inhibits colorectal cancer progression and promotes apoptosis by increasing M1-type macrophages and activating the Bax/Bcl-2/caspase-3/PARP pathway.

Condition: Cancer, Carcinoma, Colon

Low‐dose naltrexone in Hailey–Hailey disease: the importance of dosing

Condition: Hailey Hailey, Hailey-Hailey, Pemphigus, Skin

Low-Dose Naltrexone for the Treatment of Fibromyalgia: Investigation of Dose-Response Relationships [Online ahead of print]

Condition: Fibromyalgia

Enkephalin Therapy Improves Relapsing-Remitting Multiple Sclerosis

Condition: Multiple Sclerosis

Low-dose Naltrexone as a Treatment for Chronic Fatigue Syndrome

Condition: Chronic Fatigue Syndrome

Low-Dose Naltrexone Reduces Symptoms in Stiff-Person Syndrome

Condition: Stiff Person

Improvement of Hailey-Hailey Disease With Low-Dose Naltrexone

Condition: Hailey-Hailey

The Lowdown on Low-Dose Naltrexone

Condition: Dermatitis, Hailey Hailey, Hailey-Hailey, Lichen, Pemphigus, Pruritus, Psoriasis, Skin

Opioid-induced Hypogonadism: Pathophysiology, Clinical and Therapeutics Review

Condition: Opiod

The effect of low-dose naltrexone on solid Ehrlich carcinoma in mice: The role of OGFr, BCL2, and immune response

Condition: Cancer

Long-term benefit from immune modulation and anti-inflammatory treatment in metastatic mesothelioma

Condition: Cancer

Very Low Dose Naltrexone in Opioid Detoxification: A Double-Blind, Randomized Clinical Trial of Efficacy and Safety

Condition: Opiod

Low-dose naltrexone in the treatment of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)

Condition: CFS, Fatigue, ME, ME/CFS

Dose Escalation of Naltrexone to Reduce Stress Responses Associated With Opioid Antagonist Induction: A Double-blind Randomized Trial

Condition: Osteoporosis

Naltrexone Restores Impaired Transient Receptor Potential Melastatin 3 Ion Channel Function in Natural Killer Cells From Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients

Condition: Fatigue, ME, ME/CFS

Hailey-Hailey Disease with Superimposed Eczema Herpeticum Caused by Herpes Simplex Virus Type 2 Infection in a Burn Unit: A Case Report and Literature Review

Condition: Eczema, Hailey Hailey, Hailey-Hailey, Herpes

Microglial Phagocytosis of Neurons: Diminishing Neuronal Loss in Traumatic, Infectious, Inflammatory, and Autoimmune CNS Disorders

Condition: Autoimmune

In vitro evaluation of Naltrexone HCl 1% Topical Cream in XemaTop™ for psoriasis

Condition: Psoriasis, Skin

Low-dose naltrexone safe, effective for neuropathic corneal pain

Condition: Dry Eye, Pain

Low-Dose Naltrexone Evaluated for Neuropathic Corneal Pain

Condition: Eye, Neuropathy, Pain

In vitro evaluation of Naltrexone HCl 1% Topical Cream in XemaTop™ for psoriasis

Condition: Psoriasis

Changes in the consumption of antiepileptics and psychotropic medicines after starting low dose naltrexone: A nation-wide register-based controlled before-after study

Condition: Depression, Epilepsy

Correction: Low dose naltrexone: Effects on medication in rheumatoid and seropositive arthritis. A nationwide register-based controlled quasi-experimental before-after study

Condition: Arthritis, Rheumatoid, Rheumatoid arthritis

A Retrospective Review of Patients Prescribed Low Dose Naltrexone for Chronic Pain at a Single Institution

Condition: Pain

Safety and tolerability of ALO-02 (oxycodone hydrochloride and sequestered naltrexone hydrochloride) extended-release capsules in older patients: a pooled analysis of two clinical trials

Condition: Opiod, Pain

Corrigendum: The Effect of Low-Dose Naltrexone on Medication in Inflammatory Bowel Disease: A Quasi Experimental Before-and-After Prescription Database Study

Condition: IBD, Inflammatory Bowel Disease

Clinically utilized kappa-opioid receptor agonist nalfurafine combined with low-dose naltrexone prevents alcohol relapse-like drinking in male and female mice

Condition: Alcohol, Substance Use

Low-Dose Naltrexone-Induced Remission in Hailey-Hailey Disease Maintained in Remission with Topical Combination of Ketamine and Diphenhydramine

Condition: Hailey Hailey, Hailey-Hailey, Pemphigus, Skin

Low-dose naltrexone: a novel adjunctive treatment in symptomatic alopecias?

Condition: Alopecia

Low-dose naltrexone therapy in benign chronic pemphigus (Hailey-Hailey disease): A case series

Condition: Hailey Hailey, Hailey-Hailey, Pemphigus, Skin

Opioid antagonists as potential therapeutics for ischemic stroke

Condition: Opiod, Stroke

Hailey-Hailey disease treated successfully with naltrexone and magnesium

Condition: Hailey Hailey, Hailey-Hailey, Pemphigus, Skin

Naltrexone for the Treatment of Darier and Hailey-Hailey Diseases

Condition: Darier, Hailey Hailey, Hailey-Hailey, Pemphigus, Skin

Interaction of opioid growth factor (OGF) and opioid antagonist and their significance in cancer therapy

Condition: Cancer, Opiod, Pain