Conditions Where Low Dose Naltrexone (LDN) Could be of Benefit.

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The conditions are listed below, select the category a condition come under to open up a further list:

Find all the information on one for conditions we hold from LDN Clinical Trials/Studies and Articles, Q&A's Conference Presentations, Interviews, Documentaries etc

To watch interviews and conference presentations covering a range of conditions click here

  • Autoimmune cardiomyopathy
  • Autoimmune myocarditis
  • Congenital heart block
  • Coxsackie myocarditis
  • Dressler's syndrome (postmyocardial infarction syndrome)
  • Giant cell myocarditis
  • Kawasaki disease
  • Polyarteritis nodosa
  • Postpericardiotomy syndrome
  • Pyoderma gangrenosum
  • Subacute bacterial endocarditis (SBE)
  • Vasculitis

  • Complex Regional Pain Syndrome/RSD
  • Diabetic Neuropathy
  • Temporomandibular joint disorder

  • Alopecia areata
  • Alopecia universalis
  • Amyopathic Dermatomyositis
  • Anti-synthetase syndrome
  • Atopic allergy
  • Atopic dermatitis
  • Autoimmune progesterone dermatitis
  • Autoimmune thrombocytopenic purpura
  • Autoimmune urticaria
  • Bechet’s syndrome
  • Benign mucosal pemphigoid
  • Blau syndrome
  • Bullous pemphigoid
  • Cicatricial pemphigoid
  • Cutaneous leukocytoclastic angiitis
  • Darier Disease
  • Dego's disease (thrombotic vasculopathy)
  • Dercum's disease
  • Dermatitis herpetiformis
  • Dermatomyositis
  • Diffuse cutaneous systemic sclerosis
  • Discoid lupus erythematosus
  • Eczema
  • Epidermolysis bullosa acquisita
  • Erythema nodosum
  • Erythmodermic psoriasis
  • Essential mixed cryoglobulinemia
  • Familial cold autoinflammatory syndrome (FCAS)
  • Frontal Fibrosing Alopecia (FFA)
  • Hailey-Hailey Disease
  • Henoch-Schonlein purpura (HSP)
  • Herpes gestationis/pemphigoid gestationis (PG)
  • Hidradenitis Suppurativa (HS) (Acne Inversa)
  • Kawasaki disease
  • Lichen planus
  • Lichen sclerosus
  • Linear IgA disease (LAD)
  • Majeed syndrome
  • Microscopic polyangiitis
  • Morphea Mucha-Habermann disease
  • Mucha-Habermann disease, PLEVA (pityriasis lichenoides et varioliformisacuta)
  • Myositis
  • Neonatal lupus
  • Parry Romberg syndrome
  • Pemphigus vulgaris
  • POEMS syndrome
  • Progesterone dermatitis
  • Psoriasis
  • Pyoderma gangrenosum
  • Schnitzler syndrome
  • Schulman disease
  • Vogt-Koyanagi-Harada Disease

  • Autoimmune inner ear disease (AIED)
  • Churg-Strauss syndrome
  • Cogan syndrome
  • Ménière's disease
  • Susac's syndrome

  • Addison's disease
  • Autoimmune polyendocrine syndrome
  • Cushing's syndrome
  • Diabetes mellitus type 1
  • Eosinophilic esophagitis (EoE)
  • Glycogen storage disorder (GSD VII)
  • Graves' disease
  • Hashimoto's thyroiditis
  • Hypoglycaemia
  • Hypopituitary or Secondary adrenal insufficiency
  • Hypothalamic Dysfunction
  • Hypothyroidism
  • Juvenile diabetes (Type 1 diabetes)
  • Ord’s thyroiditis
  • Pituitary dysfunction
  • POEMS syndrome
  • Polyglandular syndromes type I, II, III
  • Schmidt syndrome
  • Thyroid eye disease (TED)
  • Thyroiditis

  • Autoimmune hepatitis
  • Autoimmune enteropathy
  • Autoimmune pancreatitis
  • Celiac disease
  • Churg-Strauss syndrome
  • Crohn’s disease
  • Eosinophilic gastroenteritis
  • Gastritis
  • Gastrointestinal pemphigoid
  • Gastroparesis
  • Gluten sensitivity
  • Gut dysbiosis
  • Inflammatory bowel disease (IBD)
  • Irritable bowel syndrome (IBS)
  • Lupoid hepatitis
  • Nonalcoholic steatohepatitis (NASH)
  • Mesenteric Panniculitis
  • POEMS syndrome
  • Polyarteritis nodosa
  • Primary biliary cirrhosis
  • Primary sclerosing cholangitis
  • Pyoderma gangrenosum
  • Small intestinal bacterial overgrowth (SIBO)
  • Schnitzler syndrome
  • Ulcerative colitis (UC)

  • Agammaglobulinemia
  • Antiphospholipid syndrome
  • Autoimmune aplastic anemia
  • Autoimmune hemolytic anemia
  • Autoimmune lymphoproliferative syndrome
  • Castleman's disease (CD) – lymph node hyperplasia
  • Cold agglutinin disease
  • Evans syndrome
  • Hemolytic anemia
  • Immune thrombocytopenic purpura (ITP)
  • Majeed syndrome
  • Monoclonal gammopathy of undetermined significance (MGUS)
  • Myelodysplastic syndromes
  • Neutropenia
  • Paroxysmal nocturnal hemoglobinuria (PNH)
  • Pernicious anemia (PA)
  • Pure red cell aplasia (PRCA)
  • Pyoderma gangrenosum
  • Thrombocytopenic purpura (TTP)

  • Hepatitis C
  • Primary Biliary Cholangitis

  • Amyloidosis
  • Autoimmune angioedema
  • Common Variable Immunodeficiency
  • Epstein Barr Virus
  • IgG4-related sclerosing disease
  • Juvenile myositis (JM)
  • Mast cell activation syndrome (MCAS)
  • Pernicious anemia (PA)
  • Vitiligo

  • Chagas disease
  • Complement component 2 deficiency – increase risk of infections
  • Coxsackie myocarditis
  • Herpes
  • Herpes Zoster (Shingles)
  • HIV/AIDS
  • Hypogammaglobulinemia – leads to infections
  • Lyme Disease
  • PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections)
  • Sydenham chorea

  • Adenoid Cystic Carcinoma
  • Bladder Cancer
  • Breast Cancer
  • Carcinoid Colon & Rectal Cancer
  • Cholangiocarcinoma
  • Colon Cancer
  • Esophageal carcinoma
  • Glioblastoma
  • Glioma
  • Hepatoblastoma
  • Leukemia
  • Liver cancer
  • Lung cancer (Non-small cell)
  • Lymphocytic leukemia (chronic)
  • Lymphoma (Hodgkin's and Non-Hodgkin's)
  • Malignant melanoma
  • Mesothelioma
  • Multiple myeloma
  • Neuroblastoma
  • Ovarian cancer
  • Pancreatic cancer
  • Parotid carcinoma
  • Prostate cancer (untreated)
  • Renal cell carcinoma
  • Throat cancer
  • Uterine cancer

  • Achalasia
  • Acute disseminated encephalomyelitis
  • Acute hemorrhagic leukoencephalitis
  • Adhesive Arachnoiditis
  • Alzheimer's
  • Amyotrophic Lateral Sclerosis (ALS)
  • Anti-mag IgM peripheral neuropathy
  • Autoimmune dysautonomia
  • Autoimmune encephalomyelitis
  • Autoimmune peripheral neuropathy
  • Axonal & neuronal neuropathy (AMAN)
  • Baló disease
  • Bickerstaff's encephalitis
  • Brain fog
  • Charcot-Marie-Tooth syndrome
  • Chronic inflammatory demyelinating polyneuropathy (CIDP)
  • Crackly brain middle ear myoclonus (MEM)
  • Cranial arteritis
  • Devic’s disease (neuromyelitis optica)
  • Duchesne Muscular Dystrophy
  • Dystonia
  • Electromagnetic hypersensitivity
  • Guillain-Barré syndrome
  • Hashimoto's encephalitis
  • Idiopathic inflammatory demyelinating diseases
  • Inflammatory demyelinating polyneuopathy
  • Lambert-Eaton myasthenic syndrome
  • Leaky brain
  • Migraines
  • Miller-Fisher syndrome
  • Movement disorders
  • Multifocal Motor Neuropathy (MMN) or MMNCB
  • Multiple sclerosis (MS)
  • Myalgic encephalomyelitis
  • Myasthenia gravis
  • Myelin Oligodendrocyte Glycoprotein Antibody Disorder (MOG-AD)
  • Myositis
  • Narcolepsy
  • Neuromyelitis optica
  • Neuromyotonia
  • Opsoclonus myoclonus syndrome
  • Optic neuritis
  • PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections)
  • Paraneoplastic cerebellar degeneration (PCD)
  • Parkinson’s disease
  • Parry Romberg syndrome
  • Parsonage-Turner syndrome
  • Peripheral neuropathy
  • Perivenous encephalomyelitis
  • POEMS syndrome
  • Polyarteritis nodosa
  • Postural orthostatic tachycardia syndrome (POTS)
  • Progressive inflammatory neuropathy
  • Rasmussen's encephalitis
  • Restless legs syndrome (RLS)
  • Stiff person syndrome (SPS)
  • Susac's syndrome
  • Sydenham chorea
  • Tired brain syndrome
  • Tolosa-Hunt syndrome
  • Transverse myelitis
  • Traumatic brain injury (TBI)
  • Vogt-Koyanagi-Harada Disease

  • Autoimmune retinopathy
  • Autoimmune uveitis
  • Balo disease/Balo concentric sclerosis
  • Blau syndrome
  • Cogan's syndrome
  • Devic’s disease (neuromyelitis optica)
  • Kawasaki disease
  • Ligneous conjunctivitis
  • Miller-Fisher syndrome
  • Mooren’s ulcer
  • Myelin Oligodendrocyte Glycoprotein Antibody Disorder (MOG-AD)
  • Neuromyelitis optica
  • Ocular cicatricial pemphigoid
  • Optic neuritis
  • Opsoclonus myoclonus syndrome
  • Parry Romberg syndrome
  • Pars planitis (peripheral uveitis)
  • POEMS syndrome
  • Scleritis
  • Susac's syndrome
  • Sweet's syndrome
  • Sympathetic ophthalmia (SO)
  • Thyroid eye disease (TED)
  • Tolosa-Hunt syndrome (THS)
  • Uveitis
  • Vasculitis vitiligo
  • Vogt-Koyanagi-Harada Disease

  • Addison’s disease
  • Autism
  • Celiac disease
  • Congenital heart block
  • Crohn’s disease
  • Juvenile arthritis
  • Juvenile dermatomyositis
  • Juvenile diabetes (Type 1 diabetes)
  • Juvenile idiopathic rheumatoid arthritis
  • Juvenile myositis (JM)
  • Lupus
  • Multiple sclerosis (MS)
  • Neonatal Lupus
  • Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections
  • Scleroderma
  • Type 1 diabetes
  • Ulcerative colitis (UC)

  • Alcohol use disorder
  • Anxiety
  • Depersonalization/Derealization Disorder
  • Depression
  • Dissociative Disorder
  • Dissociative identity disorder
  • General Anxiety Disorder (GAD)
  • Hypervigilance
  • Obsessive Compulsive Disorder (OCD)
  • Opioid withdrawal
  • Panic Disorder
  • Phobias
  • Post-Traumatic Stress Disorder (PTSD)
  • Postpartum Depression
  • Premenstrual Dysphoric Disorder (PMDD)
  • Social Phobia
  • Stress
  • Substance abuse disorders
  • Trichotillomania

  • Anti-synthetase syndrome
  • Asthma Churg-Strauss syndrome
  • Emphysema
  • Fibrosing alveolitis
  • Granulomatosis with Polyangiitis (formerly Wegener’s Granulomatosis)
  • Goodpasture's syndrome
  • Idiopathic pulmonary fibrosis
  • POEMS syndrome
  • Sarcoidosis

  • Anti-GBM/Anti-TBM Nephritis
  • Autoimmune orchitis
  • Autoimmune renal neuropathy
  • Berger's disease - IgA nephropathy
  • Glomerulonephritis
  • Goodpasture's syndrome
  • IgA nephropathy
  • Interstitial cystitis (IC)
  • Microscopic polyangiitis (MPA)
  • Paroxysmal nocturnal hemoglobinuria (PNH)
  • POEMS syndrome
  • Sperm & testicular autoimmunity

  • Adult Still's disease
  • Ankylosing spondylitis
  • Anti-synthetase syndrome
  • Arthritis
  • Chronic fatigue syndrome (CFS)
  • Chronic recurrent multifocal osteomyelitis (CRMO)
  • Complement component 2 deficiency – increase risk of lupus
  • CREST syndrome
  • Ehlers-Danlos Syndrome (EDS)
  • Enthesitis-related arthritis
  • Eosinophilic fasciitis
  • Fibrodysplasia ossificans progressive
  • Fibromyalgia
  • Inclusion body myositis (IBM)
  • Juvenile arthritis
  • Juvenile idiopathic arthritis
  • Juvenile rheumatoid arthritis – Still’s disease
  • Lupus erythematosus
  • Majeed syndrome
  • Mixed connective tissue disease (MCTD)
  • Morphea myositis
  • Myalgic Encephalopathy (ME)
  • Palindromic rheumatism (PR)
  • Polymyalgia rheumatica
  • Polymyositis
  • Psoriatic arthritis
  • Raynaud’s phenomenon
  • Reactive Arthritis
  • Reiter's syndrome
  • Relapsing polychondritis
  • Retroperitoneal fibrosis
  • Rheumatic fever
  • Rheumatoid arthritis
  • Sarcoidosis
  • Schnitzler syndrome
  • Scleroderma
  • Seropositive arthritis
  • Sjögren's syndrome
  • Spondylitis
  • Spondyloarthropathy
  • Subacute cutaneous lupus erythematosus (SCLE)
  • Undifferentiated connective tissue disease (UCTD)
  • Undifferentiated spondyloarthropathy

  • Sleep Issues

  • Blau syndrome
  • Churg-Strauss Syndrome (CSS) or Eosinophilic Granulomatosis (EGPA)
  • Essential mixed cryoglobulinemia
  • Giant cell arteritis (temporal arteritis)
  • Kawasaki disease
  • Leukocytoclastic vasculitis
  • Polyarteritis nodosa
  • Takayasu's arteritis
  • Temporal arteritis/Giant cell arteritis

  • Autoimmune oophoritis
  • Endometriosis
  • Healthy pregnancy – new concepts
  • Herpes gestationis/pemphigoid gestationis (PG)
  • Infertility
  • PMS (premenstrual syndrome)
  • Polycystic Ovary Syndrome (PCOS)
  • Pregnancy
  • Premenstrual syndrome (PMS)
  • Progesterone dermatitis
  • Recurrent vaginitis
  • Reduced ovarian reserve (Low AMH)
  • Vaginitis
  • Vulvodynia
  • Painful periods (Dysmenorrhea)

  • Feline AIDS
  • Feline Leukaemia
  • Postural orthostatic tachycardia syndrome (POTS)
  • Traumatic brain injury (TBI)