Double-blinded placebo-controlled cross-over pilot trial of naltrexone to treat Gulf War Illness

Fatigue: Biomedicine, Health & Behavior
09 June 2018
https://www.tandfonline.com/doi/full/10.1080/21641846.2018.1477034?scroll=top&needAccess=true

Background: 30% of Gulf War veterans developed Gulf War Illness (GWI) with chronic fatigue, pain, and neuropsychological disabilities.

Naltrexone and Scopolamine Rapidly Reduce Symptoms of Major Depressive Disorder (MDD): A Double Blinded Randomized Controlled Pilot Study

Open Journal of Depression
February 2019
https://www.scirp.org/JOURNAL/PaperInformation.aspx?paperID=89841&

Potential antidepressant role of low-dose naltrexone in a rat model of chronic unpredictable mild stress

A pilot trial of low-dose naltrexone in primary progressive multiple sclerosis

J Mult Scler
September 2008
https://www.ncbi.nlm.nih.gov/pubmed/18728058

Bernard Bihari, MD: Low-Dose Naltrexone for normalizing immune system function

Altern Ther Health Med
05 November 2013
http://todayspractitioner.com/wp-content/uploads/2013/10/Bernard-Bihari-MD-Low-dose-Naltrexone-for-Normalizing-Immune-System-Function-athm_19_2_bihari_56_65.pdf

Low-Dose Naltrexone reduces symptoms in Stiff-Person Syndrome

Med Hypotheses
April 2020
https://pubmed.ncbi.nlm.nih.gov/31954293/

Does Naltrexone Treatment Lead to Depression? Findings From a Randomized Controlled Trial in Subjects With Opioid Dependence (Abstract)

J Psychiatry Neurosci
January 2006
https://pubmed.ncbi.nlm.nih.gov/16496034/

Objective: Dysphoria and depression have been cited as side effects of the opioid antagonist naltrexone. We aimed to assess whether depressive symptoms are a clinically relevant side effect in a population receiving naltrexone as a treatment for opioid dependence.

Low Dose Naltrexone in the Treatment of Fibromyalgia (Abstract)

Curr Rheumatol Rev
2018
https://pubmed.ncbi.nlm.nih.gov/28325149/

Background: ConclusionFibromyalgia is a chronic pain disorder characterized by diffuse musculoskeletal pain, fatigue, sleep disturbance and cognitive impairment.

Naltrexone could alleviate depression symptoms in patients who relapsed while taking antidepressants

PsyPost
18 December 2016
https://www.psypost.org/2016/12/naltrexone-alleviate-depression-symptoms-patients-relapsed-taking-antidepressants-46566

The Uses of Low-Dose Naltrexone in Clinical Practice

BMJ Case Reports
January 2018
https://www.researchgate.net/publication/328997819_Issue_4_The_Uses_of_Low-Dose_Naltrexone_in_Clinical_Practice