Inexpensive Compounding of Low-Dose Naltrexone With Orange Juice

J Am Acad Dermatol
28 March 2019
https://www.practiceupdate.com/content/inexpensive-compounding-of-low-d…

Inexpensive method to formulate low-dose naltrexone (LDN) at any local pharmacy by compounding full-dose naltrexone tablets into orange juice. This formulation can be dispensed with a dropper or mixed into a larger volume of juice.
 

The Use of Naltrexone in Dermatology. Current Evidence and Future Directions

Curr Drug Targets
2019
https://pubmed.ncbi.nlm.nih.gov/30887922/

Low-dose naltrexone: a unique treatment for amyopathic dermatomyositis

Dermatol Online J
15 June 2019
https://escholarship.org/uc/item/89b75552

Dickson Chemist developed a new formulation of LDN which will hopefully improve the outcomes for patients. This new formulation is a more concentrated liquid in the form of drops which are administered under the tongue and absorbed directly from the mucosal lining of the mouth. This sublingual route produces a more rapid absorption bypassing the liver and digestive tract. There are several potential advantages to this, the drug may be more effective and will not be affected by the presence of food stuffs or the hostile environment of the gut.