Barb from Canada shares her 26-year journey with fibromyalgia, which began with chronic pain and a l

This is an excerpt from "Low-Dose Naltrexone Reduces Pain and Improves Function in Fibromyalgia"
By: Hibah Khaja, PharmD | Publish Date: November 10, 2025, Originally published in: Clinical Advisor - Rheumatology.

Low-dose naltrexone (LDN) significantly reduces pain and improves functional outcomes among patients with fibromyalgia while maintaining a favorable safety profile, according to study results presented at the American College of Rheumatology (ACR) Convergence 2025, held from October 24 to 29, in Chicago, IL.

Medscape Medical News/Features

The Off-Label Treatment That Helps Many With Fibromyalgia

Laurie Tarkan | October 29, 2025

An unlikely, decades-old drug is gaining traction as a promising off-label treatment for fibromyalgia, driven by a handful of studies and a growing number of anecdotal reports.

Living with Lupus and Fibromyalgia: Kerry's Personal Journey

Sunita Shares her Multiple Conditions and How LDN has Helped

Sunita from the United States who takes LDN for fibromyalgia depression dry eye and dry mouth, her journey start end of 2013 living in a house with mold. She has Thyroid issues, Sjogrn's syndrome and LDN changed her life.

Low-Dose Naltrexone for Severe Fibromyalgia Syndrome: A Report of a Case With Two-Year Follow-Up

Ulrich Moser | Published: May 10, 2025

https://www.cureus.com/articles/366372-low-dose-naltrexone-for-severe-fibromyalgia-syndrome-a-report-of-a-case-with-two-year-follow-up#!/

Low-dose naltrexone shows promise for long COVID

New Zealand Doctor Rata Aotearoa

David Codyre

Wednesday 8 January 2025

Psychiatrist David Codyre reviews the growing evidence for low-dose naltrexone in the treatment of functional syndromes such as fibromyalgia, chronic fatigue and long COVID

Key points, In low doses (typically 3–4.5mg daily), naltrexone appears to modulate  ... 

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