Generalized familial benign chronic pemphigus (Hailey-Hailey disease) treated successfully with low-dose naltrexone

JAAD Case Rep
16 August 2018
https://pubmed.ncbi.nlm.nih.gov/30167446/

Utility of Naltrexone Treatment for Chronic Inflammatory Dermatologic Conditions: A Systematic Review

JAMA Dermatol
01 February 2019
https://pubmed.ncbi.nlm.nih.gov/30484835/

The uses of naltrexone in dermatologic conditions

J Am Acad Dermatol
June 2019
https://pubmed.ncbi.nlm.nih.gov/30582992/

Background: Naltrexone in standard and reduced doses is efficacious in many inflammatory and acantholytic disorders.

Objective: We summarized the current data of naltrexone that are relevant to dermatologic practice.

Variable response to low‐dose naltrexone in patients with Darier disease: a case series

J Eur Acad Dermatol Venereol
03 February 2019
https://onlinelibrary.wiley.com/doi/abs/10.1111/jdv.15457

Inexpensive Compounding of Low-Dose Naltrexone With Orange Juice

J Am Acad Dermatol
28 March 2019
https://www.practiceupdate.com/content/inexpensive-compounding-of-low-d…

Inexpensive method to formulate low-dose naltrexone (LDN) at any local pharmacy by compounding full-dose naltrexone tablets into orange juice. This formulation can be dispensed with a dropper or mixed into a larger volume of juice.
 

The Use of Naltrexone in Dermatology. Current Evidence and Future Directions

Curr Drug Targets
2019
https://pubmed.ncbi.nlm.nih.gov/30887922/

Use of low-dose naltrexone in the treatment of severe Hailey-Hailey disease: One case report

Dermatol Ther
22 April 2019
https://pubmed.ncbi.nlm.nih.gov/30958613/

Naltrexone for the Treatment of Darier and Hailey-Hailey Diseases

J Cutan Med Surg
24 July 2019
https://www.researchgate.net/publication/334649366_Naltrexone_for_the_Treatment_of_Darier_and_Hailey-Hailey_Diseases

Low-Dose Naltrexone-Induced Remission in Hailey-Hailey Disease Maintained in Remission with Topical Combination of Ketamine and Diphenhydramine

Indian Dermatol Online J
28 August 2019
https://pubmed.ncbi.nlm.nih.gov/31544078/

Hailey-Hailey disease treated successfully with naltrexone and magnesium

JAAD Case Rep
29 August 2019
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728728/