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Evaluation of Low-Dose Naltrexone for Chronic Pain Management
February 2025 Journal of Pain & Palliative Care Pharmacotherapy
Alexa Spargo, Lauren Gonser & Brittany Faley
Abstract
Co-administration of low-dose-Naltrexone and Carbamazepine remarkedly ameliorate allodynia and cognitive deficit in a rat model of trigeminal neuralgia
Yeganeh Naderi, Monavareh Soti, Masoud Soltani, Yasaman Naderi, Kristi A. Kohlmeier & Mohammad Shabani
Scientific Reports volume 15, Article number: 31335 (26th August 2025)
Ultra-Low-Dose Opioid Antagonists Enhance Opioid Analgesia and Reduce Tolerance
By Hoau-yan Wang
2009, Opiate Receptors and Antagonists
Mark's Chronic Pain and LDN Journey
Low-Dose Naltrexone for Managing Pain and Autonomic Symptoms in Patients With Dysautonomia
Zapata N, Georgiadi E, Cantrell C, et al. (June 22, 2025)
Cureus 17(6): e86538. doi:10.7759/cureus.86538
Breakthrough book spotlights the life-changing potential of low dose naltrexone (LDN) for chronic pain and complex conditions
The Phoenix Newspaper | Health and Wellbeing
8th June 2025
With millions suffering silently from chronic pain and complex conditions, The LDN Book 4: Case Studies in Chronic Pain (LDN Research Trust) is offering timely and life-changing insights into one of medicine's best-kept secrets — low dose naltrexone (LDN).
Commentary: Article May 12, 2025
Can Low-Dose Naltrexone Fill the Gaps in Palliative Pain Management?
Author(s):Emma Murter, PharmD, MPH, Madison N. Irwin, PharmD, BCPS
Low-Dose Naltrexone in Pain Management and Inflammatory Disorders
Nature Research Intelligence
November 7, 2024
By Lauren Massaro
https://www.drugtopics.com/view/q-a-pharmacists-champion-nonopioid-pain-management-strategies
Melissa Durham, PharmD, MACM, reveals how pharmacists are uniquely positioned to counsel patients on nonopioid pain management.
Pain specialist Dr Chris Kleronomos from Oregon us talks about how he used Ultra low dose naltrexone and LDN in his clinic.Dr.