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Low-Dose Naltrexone Use for Patients with Chronic Regional Pain Syndrome: A Systematic Literature Review
Pain Physician
July 2021
https://pubmed.ncbi.nlm.nih.gov/34213865/
Background: Complex regional pain syndrome is a rare, neuropathic disorder that affects fewer than 200,000 individuals in the United States annually. Current treatments often focus on pain management and fall short of relieving symptoms of pain and dystonia in patients.
Naltrexone is neuroprotective against traumatic brain injury in mu opioid receptor knockout mice
CNS Neurosci Ther
21 May 2021
https://pubmed.ncbi.nlm.nih.gov/34018697/
Preclinical and clinical studies into the bioactivity of low-dose naltrexone (LDN) for oncotherapy
Int Immunopharmacol
11 May 2021
https://pubmed.ncbi.nlm.nih.gov/33989971/
Utilization of Low-Dose Naltrexone for Burning Mouth Syndrome: A Case Report
A A Pract
17 May 2021
https://pubmed.ncbi.nlm.nih.gov/33999864/
Efficacy and safety of low-dose naltrexone in painful diabetic neuropathy: A randomized, double-blind, active-control, crossover clinical trial
J Diabetes
20 May 2021
https://pubmed.ncbi.nlm.nih.gov/34014028/
Reported Benefits of Low-Dose Naltrexone Appear to Be Independent of the Endogenous Opioid System Involving Proopiomelanocortin Neurons and Beta-Endorphin
eNeuro
24 May 2021
https://www.eneuro.org/content/early/2021/05/21/ENEURO.0087-21.2021
Addiction Medication Promising for Chronic, Refractory Pain
Medscape Medical News
01 May 2021
https://www.medscape.com/viewarticle/950263
Preliminary data from a retrospective chart review of patients with chronic pain showed those who received LDN experienced significant improvement in both pain and disability.
LDN And Rheumatoid Arthritis
MITECHNEWS.COM
30 March 2021
https://mitechnews.com/guest-columns/ldn-and-rheumatoid-arthritis/
Reports from 23andme/CureTogether suggest that LDN (low dose naltrexone) is among the most effective and potent treatments for Rheumatoid Arthritis. Regular and consistent consumption of LDN significantly reduced the need to use other painkillers and disease modifying drugs among Rheumatoid Arthritis patients.