In patients with fibromyalgia, is low-dose naltrexone effective in alleviating pain, and does it decrease use of oral opioids?

Evidence-Based Practice
June 2017
https://journals.lww.com/ebp/Abstract/2017/06000/In_patients_with_fibromyalgia,_is_low_dose.13.aspx

Double-blinded placebo-controlled cross-over pilot trial of naltrexone to treat Gulf War Illness

Fatigue: Biomedicine, Health & Behavior
09 June 2018
https://www.tandfonline.com/doi/full/10.1080/21641846.2018.1477034?scroll=top&needAccess=true

Background: 30% of Gulf War veterans developed Gulf War Illness (GWI) with chronic fatigue, pain, and neuropsychological disabilities.

Low Dose Naltrexone for Neuropathic Pain Related to an Electrical Burn Injury: A Case Study

J Pain
April 2019
https://www.sciencedirect.com/science/article/pii/S1526590019306595

Low-Dose Naltrexone in the Treatment of Fibromyalgia: A Retrospective Analysis

Curr Rheumatol Rev
2018
https://pubmed.ncbi.nlm.nih.gov/28325149/

Background: Fibromyalgia is a chronic pain disorder characterized by diffuse musculoskeletal pain, fatigue, sleep disturbance and cognitive impairment.

Naltrexone Restores Impaired Transient Receptor Potential Melastatin 3 Ion Channel Function in Natural Killer Cells From Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients

Front. Immunol
31 October 2019
https://www.frontiersin.org/articles/10.3389/fimmu.2019.02545/full

Low-Dose Naltrexone Evaluated for Neuropathic Corneal Pain

MPR First Report
14 October 2019
https://www.empr.com/home/mpr-first-report/aao/aao-2019/low-dose-naltrexone-evaluated-for-neuropathic-corneal-pain/

Low-dose naltrexone in the treatment of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)

Fatigue: Biomedicine, Health & Behavior
19 November 2019
https://www.tandfonline.com/doi/abs/10.1080/21641846.2019.1692770?journalCode=rftg20

Low-Dose Naltrexone (LDN)-Review of Therapeutic Utilization

Medical Sciences
21 September 2018
https://pdfs.semanticscholar.org/c495/7df14b181c4ae963a80fdeaf38c5cbb1a9e3.pdf?_ga=2.217655315.460139797.1583212532-762170649.1583212532

Augmentation of spinal morphine analgesia and inhibition of tolerance by low doses of mu- and delta-opioid receptor antagonists

Br J Pharmacol
July 2007
https://pubmed.ncbi.nlm.nih.gov/17502848/

Preliminary study of altered skin temperature at body sites associated with self-injurious behavior in adults who have developmental disabilities (Abstract)

Am J Ment Retard
July 2001
https://pubmed.ncbi.nlm.nih.gov/11414874/

Erratum: in Table 1 a column heading was inadvertently omitted. See Am J Ment Retard 2001 Sep;106(5):469