Low dose naltrexone in refractory neuropathic pain associated with autoimmune transverse myelitis

J Pain
01 April 2015
https://www.jpain.org/article/S1526-5900(15)00354-5/fulltext

A case of transverse myelitis (TM) with secondary central pain syndrome refractory to multiple pain medications and immune-modulation therapies, which responded to low dose (3-4.5 mg) Naltrexone.

 

Endogenous opioid inhibition of proliferation of T and B cell subpopulations in response to immunization for experimental autoimmune encephalomyelitis

BMC Immunol
24 April 2015
https://pubmed.ncbi.nlm.nih.gov/25906771/

Initial Findings of an Open-Label Trial of Low-Dose Naltrexone for Symptomatic Mesenteric Panniculitis

J Clin Gastroenterol
October 2015
https://www.academia.edu/28700218/Initial_Findings_of_an_Open_Label_Trial_of_Low_Dose_Naltrexone_for_Symptomatic_Mesenteric_Panniculitis

Low Dose Naltrexone (LDN): New in the treatment of chronic pain syndromes. What really matters – reduced pain or increased energy?

Neuro Sciences
15 October 2015
https://www.jns-journal.com/article/S0022-510X(15)01775-X/fulltext

No Antagonists for an Antagonist: One Pitfall of Chronic Oral Low-Dose Naltrexone

Pain Medicine
December 2015
http://www.painmedicinenews.com/download/Casespmnse1215_WM.pdf

A 48 year old man with 10 years of chronic abdominal pain following an open repair of an abdominal aortic aneurysm was treated with low dose naltrexone 1.5mg/day for 3 years with satisfactory results.

 

Off-Label, Low-Dose Naltrexone for Refractory Painful Diabetic Neuropathy

Pain Medicine
April 2016
http://painmedicine.oxfordjournals.org/content/early/2015/11/25/pm.pnv009

A novel glial cell inhibitor, low dose naltrexone, reduces pain and depression, and improves function in chronic pain: A CHOIR study

J Pain
01 April 2016
http://www.jpain.org/article/S1526-5900(16)00425-9/fulltext