Low-Dose Naltrexone Reverses Facial Mechanical Allodynia in a Rat Model of Trigeminal Neuralgia

Neurosci Lett
25 Sept 2020
https://pubmed.ncbi.nlm.nih.gov/32673692/

Low-Dose Naltrexone for Chronic Pain: Update and Systemic Review

Curr Pain Headache Rep
26 Aug 2020
https://pubmed.ncbi.nlm.nih.gov/32845365/


Purpose of review: The purpose of this review is to evaluate and explain our current understanding of the clinical use of low-dose naltrexone in the treatment of chronic pain.

Experimental autoimmune encephalopathy (EAE)-induced hippocampal neuroinflammation and memory deficits are prevented with the non-opioid TLR2/TLR4 antagonist (+)-naltrexone

Behav Brain Res
01 Jan 2021
https://pubmed.ncbi.nlm.nih.gov/32905811/

Ameliorative response to detoxification, psychotherapy, and medical management in patients maintained on opioids for pain

Am J Addict
Oct 2017
https://pubmed.ncbi.nlm.nih.gov/28800186/

Biased Opioid Antagonists as Modulators of Opioid Dependence: Opportunities to Improve Pain Therapy and Opioid Use Management  (Abstract)

Molecules
11 Sept 2020
https://pubmed.ncbi.nlm.nih.gov/32932935/

Intranasal Low-Dose Naltrexone Against Opioid Side Effects: A Preclinical Study (Abstract)

Front Pharmacol
18 Sept 2020
https://pubmed.ncbi.nlm.nih.gov/33071790/

Use of low-dose naltrexone in the management of chronic pain conditions: A systematic review (Abstract)

J Am Dent Assoc
December 2020
https://pubmed.ncbi.nlm.nih.gov/33228882/

Background: The authors aimed to evaluate the efficacy of low-dose naltrexone in the management of chronic pain conditions and determine its potential use in orofacial pain management.

Low-dose naltrexone for the treatment of fibromyalgia: findings of a small, randomized, double-blind, placebo-controlled, counterbalanced, crossover trial assessing daily pain levels

Arthritis Rheum
February 2013
https://pubmed.ncbi.nlm.nih.gov/23359310/​​​​​​​

Low-Dose Naltrexone: An Inexpensive Medicine for Many Ills?

Medscape Medical News
11 Mar 2020
https://www.medscape.com/viewarticle/926611?src=WNL_trdalrt_201027_MSCPEDIT&uac=267476HJ&impID=2640101&f