The uses of naltrexone in dermatologic conditions

J Am Acad Dermatol
June 2019
https://pubmed.ncbi.nlm.nih.gov/30582992/

Background: Naltrexone in standard and reduced doses is efficacious in many inflammatory and acantholytic disorders.

Objective: We summarized the current data of naltrexone that are relevant to dermatologic practice.

The Use of Naltrexone in Dermatology. Current Evidence and Future Directions

Curr Drug Targets
2019
https://pubmed.ncbi.nlm.nih.gov/30887922/

Low-dose naltrexone: a unique treatment for amyopathic dermatomyositis

Dermatol Online J
15 June 2019
https://escholarship.org/uc/item/89b75552

Severe pruritus of cholestasis in disseminated cancer: developing a rational treatment strategy. A case report

J Pain Symptom Manage
January 2005
https://www.sciencedirect.com/science/article/pii/S0885392404003914

The Lowdown on Low-Dose Naltrexone

Cutis
January 2020
https://mdedge-files-live.s3.us-east-2.amazonaws.com/files/s3fs-public/CT105001017_e.PDF

Dickson Chemist developed a new formulation of LDN which will hopefully improve the outcomes for patients. This new formulation is a more concentrated liquid in the form of drops which are administered under the tongue and absorbed directly from the mucosal lining of the mouth. This sublingual route produces a more rapid absorption bypassing the liver and digestive tract. There are several potential advantages to this, the drug may be more effective and will not be affected by the presence of food stuffs or the hostile environment of the gut.