The use of Low-Dose Naltrexone (LDN) as a novel anti-inflammatory treatment for chronic pain

Clin Rheumatol
15 February 2014
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962576/

Low Dose Naltrexone in the Treatment of Fibromyalgia (Abstract)

Curr Rheumatol Rev
2018
https://pubmed.ncbi.nlm.nih.gov/28325149/

Background: ConclusionFibromyalgia is a chronic pain disorder characterized by diffuse musculoskeletal pain, fatigue, sleep disturbance and cognitive impairment.

The Uses of Low-Dose Naltrexone in Clinical Practice

BMJ Case Reports
January 2018
https://www.researchgate.net/publication/328997819_Issue_4_The_Uses_of_Low-Dose_Naltrexone_in_Clinical_Practice

Off-label, Low-Dose Naltrexone for Refractory Chronic Low Back Pain

Pain Med
May 2014
https://europepmc.org/article/med/24967470

Low‐dose naltrexone for the treatment of fibromyalgia: Findings of a small, randomized, double‐blind, placebo‐controlled, counterbalanced, crossover trial assessing daily pain levels

Arthritis & Rheumatology
28 January 2013
https://onlinelibrary.wiley.com/doi/full/10.1002/art.37734

Serious adverse events reported in placebo randomised controlled trials of oral naltrexone: a systematic review and meta-analysis


BMC Medicine
15 January  2019
https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-018-1242-0

 

Dr. Armin Schwarzbach, Infections in Cancer and Autoimmune Disorders. Presented by Markus Berger.

Low-Dose Naltrexone for Chronic Pain: Update and Systemic Review

Curr Pain Headache Rep
26 Aug 2020
https://pubmed.ncbi.nlm.nih.gov/32845365/


Purpose of review: The purpose of this review is to evaluate and explain our current understanding of the clinical use of low-dose naltrexone in the treatment of chronic pain.