Brief report: six months continuation treatment in naltrexone-responsive children with autism... (Abstract)

Brief report: six months continuation treatment in naltrexone-responsive children with autism: an open-label case-control design

J Autism Dev Disord
April 1999
https://pubmed.ncbi.nlm.nih.gov/10382138/

This paper reports on a six-month continuation treatment with naltrexone of six children with autism, previously found to be responsive to naltrexone in a four-week trial. Results indicated the moderate hyperactivity-reducing effect of naltrexone was maintained during the six-month continuation treatment but no additional gains in the domains of social interaction, communication, or stereotypic behavior were observed.

Keywords: Autism, Behavior Problems, Children, Drug Therapy, Hyperactivity, Outcomes of Treatment