Can Naltrexone and paricalcitol be combined in transdermal pericalcidol? Iis the 1-25 vitamin D2 less calciumic than calcitrio? Pericastal is commonly used in renal patients. It may be used to treat long-term COVID by stimulating vitamin D receptors without evoking hypercalcemia in the serum.
To answer that question I have no experience compounding with it. It's not available as a compounding API so we've not seen it used in topical applications. I have no knowledge of it. I do know that the one form that I did present to you earlier that had Naltrexone along with diphenhydramine and vitamin D3 was useful and it is very stable formulation for topical use. So I would imagine that it could be done but I just don't have a source of it. We've never formulated with it in our formulations. I couldn't really give you an experience on that. I don't want to give you misinformation. I'll leave it at that and let you figure it out. If you can find a source maybe you could formulate with it or get your compounding pharmacy to formulate with it. But it has to be a viable API Source from a reputable vendor. Something that has a monograph that we could utilize in compounding.