Can Low Dose Naltrexone (LDN) and Pericalcitol be Combined in Transdermal Periacidol? 

Can Naltrexone and  paricalcitol be combined in transdermal pericalcidol?  Iis the 1-25 vitamin D2 less calciumic than calcitrio? Pericastal is commonly used in renal patients.  It may be used to treat long-term COVID by stimulating vitamin D receptors without evoking hypercalcemia in the serum. 

To answer that question I have no experience compounding with it.  It's not available as a compounding API so we've not seen it used in topical applications.  I have no knowledge of it.   I do know that the one  form that I did present to you earlier that had Naltrexone along with diphenhydramine and vitamin D3 was useful and it is very stable formulation for topical use.  So I would imagine that it could be done but I just don't have a source of it.  We've never formulated with it in our formulations.  I couldn't really give you an experience on that.  I don't want to give you misinformation.  I'll leave it at that and let you figure it out.  If you can find a source maybe you could formulate with it or get your compounding pharmacy to formulate with it.  But it has to be a viable API Source from a reputable vendor.  Something that has a monograph that we could utilize in compounding.