Can Low Dose Naltrexone (LDN) be taken with Lyrica?

LDN Specialist Pharmacist Michelle Moser
Pharmacist, Michelle Moser 

Can Low Dose Naltrexone (LDN) be taken with Lyrica?

Would really appreciate your views on taking LDN together with Lyrica for pain relief. 

So Lyric is a controlled substance in the United States and it works very well for nerve pain in a lot of people. 

Now some people don't find that it works well at all and to me, that means that there's something else going on. So any time that someone has nerve pain, there's a lot of inflammation that is impinging that nerve or impinging the muscle that the nerve is conducting through, or there is some spinal cord impingement. 

So all the nerves come down the spinal cord, move out through the different bony structures of the spine column to then go out to the body parts. In that, some people will feel pain in their fingers or feel pain and their feet, but really the problem is back in the central column of the spine. 

So the nerve, you may feel it here, but the impingement is actually way back at the spinal column. So Low Dose Naltrexone can be used, does not cause any drug interactions, doesn't cause issues with Lyrica whatsoever. 

Again, start low, go slow, and go from there.