Can Low Dose Naltrexone (LDN) cause TSH Antibodies to Rise?

LDN Specialist
LDN Specialist Pharmacist Michelle Moser and Dr Sam Lebsock

Can Low Dose Naltrexone (LDN) cause TSH Antibodies to Rise?

With Hashimoto how long after starting LDN can you expect thyroid antibodies to start coming down?  This issue was addressed by Dr Sarah Zielsdorf.  There are a couple things going on.  Antibodies actually go up possibly because the dose is too high and possibly there may be some other issues going on with that individual that um also need to be addressed. There could be a nutrient or micronutrient deficiencies.  Usually when someone starts LDN and they have Hashimoto thyroiditis they have an entire thyroid panel every 4-6 weeks.  It is not uncommon that thyroid function starts to get better and and head toward normal and with that your typical dose or the dose you've been started on either levothyroxine or liothyronine or porcine derived thyroid USP may now be too high.  It is important that people are not over medicated with thyroid because we don't want a racing heart, or headaches and we certainly don't want people to head toward osteopenia and osteoporosis (but those issues are generally from uncontrolled low thyroid).  Antibodies usually start coming down four to six weeks after starting LDN.  If they go up then there's other micronutrient issues.