Can Low Dose Naltrexone (LDN) increase cortisol?

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LDN Specialist Pharmacist Michelle Moser
LDN Specialist Pharmacist Michelle Moser

 

Can Low Dose Naltrexone (LDN) increase cortisol?...............can ldn increase cortisol i have high night cortisol so i don't want to increase it anymore if it does what would you recommend taking it so the mechanisms by which cortisol are elevated have a lot to do with stress situations but also even interaction between how the chemicals are moving in the brain whether or not there's enough melatonin some of the other substrates like vitamin d but also even going back to the sex steroid hormones right so oral progesterone can increase nighttime cortisol if it's if it's too high there's a wide variety of things going on here directly ldn i don't see increases nighttime cortisol uh if anything i think it helps to reduce the inflammatory responses due to elevated cortisol whether it's direct or indirect um you can make a case for either of those but when but the question specifically was does it increase cortisol and i don't see that i actually see that it helps with the benefits of high cortisol to help reduce the inflammation due to elevated cortisol so if it does what time would you recommend taking it i still recommend taking it at bedtime just because when the body's at rest you tend to have more restorative sleep you tend to have more um opportunity for the endorphins to increase and just kind of go from there