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Can Low-Dose Naltrexone Offer Pain Relief?
MedPage Today
27 June 2022
https://www.medpagetoday.com/opinion/pain-points/99457
The most intriguing and encouraging finding is that so-called neuropathic pain may benefit even more from LDN than the so-called nociceptive or inflammatory pain states that it has been directed at over the past 20 years. Growing evidence suggests TLR-4 is involved in central sensitization, and thus it makes sense that LDN might be one of the smarter ways of addressing this widespread problem.