Can you dissolve standard tablets in water, keep it refrigerated and use it with a syringe for exact precise dosing?

Can you dissolve standard tablets in water, keep it refrigerated and use it with a syringe for exact precise dosing? 

Here's the problem, and now I have to speak about this from the compliance and regulatory aspect.  Tap water we don't generally use for compounding because the question was, can I dissolve a tablet in water and then do precise dosing?  

Although it is cheap, it is fraught with difficulty because in each tablet there's a number of components that may be in there, but actually it's the water. I'm worried about water. Your tap water that's potable for drinking isn't as clean as pharmaceutical use water. 

And number two, it doesn't have a preservative. So, if you're doing these really, really, really small doses, the biggest problem that I see is you have microbial contamination in that water after about three or four days. And if you're dipping a syringe in and out, you're just running the risk of higher and higher contamination. And then eventually you're just drinking bacterial loads. So that's my only concern. 

Can you do it? I would work with a compounder. We actually have formulations in our database that have six months beyond use states in liquid formats for naltrexone. And so, if you work with a good compounder, they can actually find a formula that can give you a six month beyond use date with a preservative. You can do that exact dosing and that's still cheap. And they can use actual pure products. 

We know the standard concentration of solution in commercial products. Please let me be clear. There is a discrepancy that they are allowed in the production of their products, even in their own quality assurance. They can have a range of +/- 10% of label stated claim. That's actually a USP standard that commercially manufactured products can do. 

So, a 50 mg tablet can have anywhere from 45 to 55 mg of Naltrexone and from lot to lot it's lasting you say, three months, and you go in for another tablet, you can have that variability from tablet to tablet. 

Your compounding pharmacy, they have a scale. They weigh their naltrexone directly, so they have much more control over your exact dosing. So, although it's cheap, now I'm gonna say this, there's a lot of things that are cheap but that aren't as good. And so, it's your health. 

Can you? Yes, but I would use distilled water at a minimum and I would get some sort of preservative into that system. And then you're going to have to look at your consistency there. 

So can you, yes. Should you? would I? No. I'd work with a compounding pharmacist. Say to them, make me a water suspension that tastes okay because I want more exact dosing for me and the microdosing would work if I can have it in a liquid system. And tell them Sebastian said you can do it. And if they can't do it, go find another compounder.