Can you suggest other medicines after a bad reaction to Xoliar?

Can you suggest other medicines after a bad reaction to Xoliar?

Reacted badly to the fifth Xolar injection. It's tough. I mean, it sounded like it might have been good to begin with, but then people can get antibodies to the injection medicine. So it's a problem. 

And then the other problem is you're injecting something that's not pure IgE, anti-IgE rather. It's got other suspensions and chemicals, but there's no way that you're going to get this compounded. So, I would just say, you know, time to go to stronger meds, Hydroxyurea, Imatinib, Toficininib, potentially even drugs like the biological drugs used for inflammatory bowel disease depending on what you have going.