Do all forms of LDN have fillers? Can you explain why LDN needs fillers? 

Do all forms of LDN have fillers?

This is one of the most commonly asked questions. There's a lot of misinformation out there on the internet, and I can't stress to you how much having a relationship with your prescriber or your pharmacy is important and not to believe everything you see on the internet.

So, in order to make a pharmaceutical formulation stable, and to make it safe, and make sure that it doesn't go off or grow bacteria, almost everything needs to have some sort of “Filler”. So, there are minute quantities of fillers in almost everything. 

And fillers can be everything from e-numbers to colorants to things like glycerin. There are some naltrexone tablets, for example, that contain lactose. We have obviously worked over the years to make sure that nothing that we make contains lactose because people react very commonly to lactose. There are a great number of people who ask about fillers because they read on the internet that some people are chemically sensitive and must be avoid this, this and this.

Generally, the number of micrograms of fillers that you're going to get in most forms of LDN are so insignificant that the benefit of the LDN is going to greatly outweigh any possible reaction you're going to have to the tiny, tiny, minuscule amounts of filler. But we do see for people who have chemical sensitivity, that the capsules are probably the lowest in content and fillers. So there's barely any colorants, barely any other ingredients other than naltrexone and some powder. But the sublingual form, as a liquid, is the most flexible dosage mechanism that has the least number of preservatives or fillers as they're discussed. 

So another question: Can you explain why LDN needs fillers? 

LDN needs fillers because you couldn't possibly measure milligrams. You wouldn't be able to see it on a spoon. You wouldn't be able to measure out from powder to take an individual dose accurately. So it needs to be scaled up to a macro scale, so we can make sure you get an accurate and reasonable dose. You also need fillers in many medications to preserve stability so that it lasts longer than a week because bacteria are all around us and they love eating anything with sugar in it, or they love eating or digesting any molecules that they possibly can, including drugs. And so there are fillers acquired in a great number of medications, although we try and minimize them, and keep them to the absolute bare minim for LDN, that is the reason for the fillers.