Do Compounding Pharmacies Make Low Dose Naltrexone (LDN) Nasal Spray? 

LDN Specialist Pharmacist Michelle Moser
LDN Specialist Pharmacist Michelle Moser

Do Compounding Pharmacies Make Low Dose Naltrexone (LDN) Nasal Spray? 

I've heard that there are some compounding pharmacies that are making nasal spray which

I was hoping we'd be able to get in the UK because we can't get sterile eye drops. I have dry eyes and I have heard if you use a nasal spray it actually helps the eyes because it goes up into the cavity.  Yes,  the nasal sprays are sometimes used for topical application because there's so much inflammation sometimes we use that to reduce inflammation.  The biofilm reactors will work so that we can then get at any type of mold or fungus that's sitting in the sinuses.  You know we have sinuses in the front and the back of our heads.  In my professional opinion I don't believe it replaces oral LDN.  I think it has its place just like topical does but technically a nasal spray is a topical just on the inside and yes our tear ducts do communicate with our nose and so sometimes as as you cry your nose runs and that's because the tears leave the the tear duct and actually drain in the back of your throat.  It can trigger other excretions from your nose.  You do have to be careful when you use a nasal spray.  If you're very inflamed it may not get into the eye but some people have done a nasal spray and they can literally feel it go into their eye because there is a direct tube, so to speak, that goes into that area.  We have seen nasal sprays work really well for mold exposure, for other toxin type issues and even some inflammatory issues associated with autoimmune disease that are affecting oral cavity and upper respiratory issues.  

Do you put Naltrexone in a nasal spray or haven't you done that yet?  We have.  It  has to be pH regulated because Naltrexone is not the easiest molecule to absorb.  We have to be careful and the pH of your gut is very different from the pH of the nasal cavities.  We need to adjust the pH to make sure that it can be absorbed and number two we're not going to irritate the nasal passages.  We don't want anything that's going to be too far off either too low a pH or too high of a pH because you don't want burning  Burning is awful.  Everybody's had burning in their nose before and it's not comfortable and that we want people to use their medications, right.  We want to make sure that they're working and that there 's a good product that we're delivering.