Do Some People React Badly to Low Dose Naltrexone (LDN)?

Have some of my patients reacted badly to LDN? I have not seen, maybe one out of all the people who've taken LDN. I don't prescribe it myself. I send that out to somebody who prescribe it because I'm not a prescribing physician. But I have to tell you, I haven't seen much. And if I do see something, it's dosage related. Okay. So if they work from half a milligram, work their way up. Okay. I usually find a place where the sweet spot is and they go too much or too little. They don't feel so hot. They don't feel so hot, and there's a sweet spot. Okay? I haven't seen, I can't think of, the last time I saw a bad reaction to LDN.