Does Low Dose Naltrexone (LDN) Work if You Take it Intermittently?

Dr Paul Anderson
Dr Paula Anderson

Does Low Dose Naltrexone (LDN) Work if You Take it Intermittently?

A patient wanted to know if you take Low Dose Naltrexone (LDN) intermittently does it still work?  The answer is that it depends on the person.  With medications, there's an idea of steady state and that's after a few days and depending what the half-life is you stop going from below to a high in your bloodstream and the median is the same every day.  With a lot of drugs if you miss a dose you know it screws up your steady state.

 

It takes Naltrexone a few days to totally be out of your system.  Every person is different when it comes to their sensitivity toward medications.  If you miss Low Dow Naltrexone for a day that indicates you are very sensitive to it. If you miss it for a day and you notice your symptoms come back you're very sensitive to its effects.