Pain associated with fibromyalgia: Benefits from low-dose naltrexone (in Italian)
In the management of pain associated with fibromyalgia, low-dose naltrexone appears to be a safe and effective treatment option. The study was conducted at the Mayo Clinic in Rochester, Minnesota in September 2022. Low-dose naltrexone appears to have systemic analgesic and anti-inflammatory effects and, as revealed by this study, it has been proposed in the management of fibromyalgia through two possible mechanisms, i.e. to improve endogenous endorphin function and to have neuroprotective and anti-inflammatory effects by suppressing the activation of the microglia.