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Dr. Dana of Love Health Direct Primary Care: A beacon of hope for Ehlers-Danlos and other chronic pain syndromes
May 13th, 2024 | By Ryan Genova
Glenside Local - Local News, Events and Buzz in Glenside, Jenkintown, Abington, Roslyn and Wyncote.
Living with Ehlers-Danlos syndrome (EDS) brings a lot of pain and other problems. But there’s a bright side: Low Dose Naltrexone (LDN) may help. LDN works in a special way. It blocks certain chemicals in your body that make you feel more pain, like interleukin 1B and interleukin 6. It also stops something called Toll-like receptor #4 (TLR #4), which is like a switch for pain in your brain. By turning off this switch, LDN helps decrease the pain you feel.
But LDN does even more than just relieve pain. It also helps with another issue common in EDS called mast cell activation syndrome (MCAS). People with EDS are 6 times more likely to have MCAS. Mast cells are like alarm bells in your body, and when they go haywire, they can cause problems like hives, asthma, and tummy troubles. LDN helps calm down these overactive mast cells, giving relief from these symptoms.
Also, there are other medicines that can help with EDS symptoms by acting on histamine receptors. Traditionally used for allergies, medicines like Claritin, Allegra, and Zyrtec can help with symptoms caused by histamine produced from mast cells. Additionally, medications like famotidine (aka Pepcid) can help with gut issues cause by histamines, and montelukast (also known as Singulair) can reduce inflammation.
Is LDN is like a superhero for managing EDS symptoms? Well, it’s promising in that it targets different parts of the body to help relieve pain and other issues.