Is fibromyalgia an endocrine/endorphin deficit disorder?... (Abstract)
Is fibromyalgia an endocrine/endorphin deficit disorder? Is low dose naltrexone a new treatment option?
The most common medications given for newly diagnosedindividuals with ﬁbromyalgia are opioids – 56%, antiepi-leptics – 29%, and tricyclic antidepressants – 21%.20If thepresented hypothesis that ﬁbromyalgia is an endocrinedisorder holds true, using opioids for pain control wouldbe the exact opposite of effective treatment, as exogenousopioids would suppress the endorphin system, eventuallyworsening symptoms. This case clearly identiﬁes deﬁni-tive response of symptoms of ﬁbromyalgia to LDN in oneindividual. LDN may be a useful, cheap, and relativelysafe medication for the management of ﬁbromyalgia.