Is fibromyalgia an endocrine/endorphin deficit disorder? Is low dose naltrexone a new treatment option?
Psychosomatics
04 April 2012
https://www.researchgate.net/publication/223962193_Is_Fibromyalgia_An_EndocrineEndorphin_Deficit_Disorder_Is_Low_Dose_Naltrexone_a_New_Treatment_Option
The most common medications given for newly diagnosedindividuals with fibromyalgia are opioids – 56%, antiepi-leptics – 29%, and tricyclic antidepressants – 21%.20If thepresented hypothesis that fibromyalgia is an endocrinedisorder holds true, using opioids for pain control wouldbe the exact opposite of effective treatment, as exogenousopioids would suppress the endorphin system, eventuallyworsening symptoms. This case clearly identifies defini-tive response of symptoms of fibromyalgia to LDN in oneindividual. LDN may be a useful, cheap, and relativelysafe medication for the management of fibromyalgia.