How do you know a Low Dose Naltrexone (LDN) dose is too high or too low?

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Deanna Wingham, MD
Dr Deanna Windham

How do you know a Low Dose Naltrexone (LDN) dose is too high or too low?

We think the dosage is too low and usually try increasing the dosage if symptom relief isn’t apparent within 3-6 months at the recommended dosage. It is typical to decrease the dosage or slow the taper up if there are any symptoms. The most common symptom by far is poor sleep when you first start although sleep improves after the dosage is stable, although patients have other minor symptoms listed on this web site.