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This video explores the mechanism of LDN as a Toll-Like Receptor (TLR) antagonist. It details how LDN modulates the immune system by antagonizing TLRs and NF-kB production, leading to reduced inflammation and potential oncogene downregulation. This information is crucial for understanding LDN's role in various cancers.
Dr. Deanna Windham, DO: What does LDN do to toll-like receptors? So if you going back again to our basic science class view, all molecules just like all of nature has both a left and a right side. So humans, human bodies has a left and a right side. Eddie, every animal has a left and right side. Every plant has a left and right side. And every medication also has a left and right side. The dextroide of nal trexone specifically is an antagonist for at least one toll-like receptor and it's reported to suppress the cytoine modulating immune system or to antag sorry excuse me I said that a little bit backwards to antagonize the suppression of the cytoine modulated immune system and to antagonize the TLR mediated production of NFCappa beta. This reduces inflammation and potentially down reggulates enkco genes or downregulates uh epigenetic changes. Yes.