How Does Low Dose Naltrexone (LDN) Affect Fertility?

LDN Specialist Pharmacist Stephen Dickson
Pharmacist Stephen Dickson

How does LDN affect fertility? It seems to be used by some doctors to help with fertility, but I don't understand how or what it helps.

I'm a pharmacist, I am not fertility expert, however, I have spoken to a number of clinics who are using it. The NeoFertility Clinic, Dr. Phil Boyle, uses LDN in fertility therapy as a general anti-inflammatory agent to help with polycystic ovaries or the production of excess inflammation in the ovaries or in the womb. Because it's a general anti-inflammatory agent, it does seem to help in a number of patients, thousands of patients we've seen with fertility issues, but it's always used in combination with other therapies, not as a monotherapy for fertility. 

This is a specialist indication where it has to be initiated, and monitored by a specialist. You can't come to us and request a prescription for LDN to help your fertility because we're not insured to cover that. It has to be through a specialist who is registered and insured to prescribe LDN for fertility. Because again, there's questions about using LDN in pregnancy and questions about the long-term issues. Who would be responsible? Not that we've ever seen any issues, but those are the questions out there.