Off-Label Meds: Promising Long COVID Treatments? (News)

Off-Label Meds: Promising Long COVID Treatments?

28 July 2023

With a lack of FDA-approved treatments, doctors who treat long COVID are turning to off-label use of drugs designed for addiction, diabetes, and other conditions.The FDA approves each drug to treat a specific condition. Off-label use, which is legal and common, allows doctors to prescribe drugs for another use.

High on the current list for off-label use to treat long COVID: low-dose naltrexone (LDN). In addition to long COVID, Dr. Azola from the Johns Hopkins Post Acute Covid Team Clinic uses LDN to treat postural orthostatic tachycardia syndrome (POTS). Other conditions where LDN is used are discussed, eg myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

No formal data exist on how widespread the use of off-label drugs for long COVID may be. But LDN is a major topic of discussion on public patient groups on Facebook.