LDN and Keytruda, can they be taken together?

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Phamacist Stephen Dickson
Pharmacist Stephen Dickson
Dickson Chemist

LDN and Keytruda, can they be taken together?

Initially, Low Dose Naltrexone (LDN) and immunotherapy drugs taken together caused concern in case of increased risk of side effects.

At the conference in 2019, we learnt many oncologists have actually used both medicines together and have reported positive results and no increase in side effects. 

In fact, one of the prominent oncologist is actually investigating an analog of LDN as an immune system prep agent, to give specifically before immunotherapy.

So while the official advice is still to remain cautious, the current clinical practice often seems to be that LDN can be taken right up to the day before Keytruda begins, then stop for the duration of treatment, starting again about 2-3 weeks after the course is completed.