LDN: A Novel Approach to Cancer

This presentation explores the potential of Low-Dose Naltrexone (LDN) in managing complex medical conditions, specifically focusing on a case involving a young woman with melanoma and severe Crohn's disease. The discussion highlights how transitioning from immunosuppressive therapies to LDN led to a remarkable improvement in Crohn's symptoms and stabilization of melanoma, suggesting a promising alternative treatment approach.

Professor Angus Dalgleish:  I think it's important to go into detail specific cases that may reveal something more than just taking LDN seems to give a better outcome. The first is a 27year-old girl with melanoma who had a past medical history over 10 years of severe Crohn's disease requiring increased steroids anti- tumor necrosis factor and while on this treatment her previous melanoma recurred with an increase in the size of the metastasis will Well, she stopped the immune suppression and I suggested adding lowd dose nrexone as I'd become aware from my research that people with Crohn's had indeed claimed benefit of lowdose nrexone and indeed this is one of the first symptoms that was noted to improve at lowdose nrexone in Dr. Bahari's clinic in New York full stop. I was able to find two randomized studies of lowd dose nrexone in Crohn's adults and children with benefit but the studies were not deemed big enough or well conducted enough for the drug to become accepted as a treatment but when this is no longer being promoted by big farmer this is not uncommon for stop I therefore persuaded her to have loders our trexone and to see if we could reduce the severe immune suppression full stop. The first thing we noted was a dramatic response to the Crohn's symptoms within two days. she for the first time was able to wake without the constant diarrhea that she would normally expect and that she indeed improved to the point where she was able to stop the anti- TNF treatment and reduce steroids. She was fairly stable after switching to lowdose nrexone for about two years. We'll stop. This is important to note she had ocular melanoma with many liver metastasis which had failed to respond to other standard treatments. So at the very least this treatment converted her disease to being static and her quality of life being good.