LDN Video Interviews and Presentations

Radio Show interviews, and Presentations from the LDN 2013, 2014, 2016, 2017, 2018 and 2019 Conferences

They are also on our    Vimeo Channel    and    YouTube Channel

Pharmacist Eric Borgeson, LDN Radio Show 2019 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Linda Elsegood: Today I'd like to welcome my guest pharmacist, Eric, Borgeson from Jersey Shore Pharmacy in New Jersey. 

Thanks for joining us today, Eric. 

Dr Eric Borgeson: Thank you for having me today. 

Linda Elsegood: Could you tell us how you got into the pharmacy? 

Dr Eric Borgeson: I originally got into pharmacy when I was 15 years old.

I got a flyer in the mail, and it's about a Lamborghini, and I wanted to drive a Lamborghini and own one. So I got into pharmacy because there were three ways to get the money required to buy the Lamborghini. It was either to inherit, which wasn't most likely going to happen or to win the lottery, which did not happen.

And the third way was to cure a disease. Then while in college, I'm getting closer and closer to a degree. In pharmacy, your ideas change, your goals change. So I became more of a person who wanted to help people and to help take care of other people and help them with their medications and getting better and staying well.

Then it was about a sports car. 

Linda Elsegood: Hmm. And have you thought any more about, you know, curing a disease? 

Dr Eric Borgeson: Not so much. I mean, curing a disease seems almost impossible at some times to say, like, to be able to come down to the exact small things that actually caused the diseases. It's easy with something like HIV or AIDS where it's a virus, and you just have to figure out how to stop the virus and stop it from replicating versus a bigger disease such as cancer or MS or Crones when there are so many factors that go into it that you don't know how to stop it. One factor is great, but when it's still there and still happens, and we still don't have the answer, you’re scratching your head as to why is this still occurring? I thought we stopped it at the source. 

Linda Elsegood: Yeah. Okay, so in your pharmacy, what do you mainly do? 

Dr Eric Borgeson: We mainly make hormone replacement therapies that involve progesterone, testosterone, estriol, Estradiol.

In that, we also make supplements for various ailment that people have. And then other various ways that people wish to take. Well, we also do the low dose naltrexone, for those patients who have fibromyalgia. We also have patients who have that and chronic fatigue syndrome that we seem to help out with that.

Linda Elsegood: Do you have many doctors that are prescribing? 

Dr Eric Borgeson: It takes a special kind of doctor to prescribe it and seems like it has to be one that believes in trying a different approach, or what their patients bring to them to try. So we have about a half dozen neurologists that do prescribe it in the area.

Also, there are few alternative practice doctors that prescribe it in the area, but we don't really have any gastroenterologists who prescribe it much. 

Linda Elsegood: Oh, okay. And we always find that the most prolific prescribers are mainly nurse practitioners. Do you have many of those in your area or, or none at all? 

Dr Eric Borgeson: We do have a lot of those in our area.

A lot of physician assistants and a lot of nurse practitioners, but they seem to really do a lot of the alternative medicines, in the sense of the low dose naltrexone, tell their patients that way. They seem to stay more towards Western medicine. The ideal of this is what the book says, how I treat my patient or X, Y, Z.

Linda Elsegood: Well, we did three talks last year like a roadshow taking LDN out there and getting pharmacies and prescribers in the area invited to come to an evening, just a two-hour talk on LDN. That has been really successful. So maybe we need to come to your area and get your prescribers to come along and, and listen - if they will listen.

Dr Eric Borgeson: Sounds like an excellent idea. 

Linda Elsegood: Yeah, that, that definitely does, isn't it? 

So what forms do you compound LDN in? 

Dr Eric Borgeson: Primarily receive. We make a capsule for us. We've made liquid for one person before, but primarily we just make LDN capsules. There was a prescriber as a psychiatrist, with interest in a low dose naltrexone cream too.

But he didn't follow through with it or never found a need for it.

Linda Elsegood: Oh, that's a shame. I mean, it seems to be working extremely well for mental health issues and also with pain, even people that are taking high doses of opioids by using ultra-low dose naltrexone. Do you have any pain specialists in your area?

Dr Eric Borgeson: We do have some, there’s a large number of pain specialists in our area, but none of them has prescribed it. But that may just be, as you said, due to a lack of education about the product. Or even just the availability. There's a bunch of us out there and trying to promote ourselves and what we do and other people out there are telling people that there are other means than traditional medicine, that there is this alternative. Sometimes it seems to fall on deaf ears or doesn't make it to the right ear. 

Linda Elsegood: Yes, true.  You know, if we can get people to come to the conference, that would be amazing. You know, watch the live stream.  But there is a lot of it. This year we had, I think, about 30 hours of pre-recorded presentations plus the two and a half days as well. It's quite a commitment to sit and watch them, or if you do have a year to watch the presentations. But nine out of 10 prescribers that watch it are so enthused by it. They will go and prescribe LDN.

And of course, as soon as they see patients doing well, they want to prescribe it more and more. 

Dr Eric Borgeson: Why don't we? Everyone has patients that they have who might be able to benefit from LDN. They're looking for something and they just can't seem to find that one magic bullet, but even something else that would help them with the bad effects of their illness and can’t think of what.

And then sometimes they're like, ‘Oh, let's try this!’ as you said. And then they're like, ‘Oh, that’s great, that worked really well for’, for example, ‘Ms Hill over there. Maybe we need it for Ms Parker over here or different elements for a different condition.’ This may help them because they had thought of it.

Linda Elsegood: Hmm, exactly. And it's, you know, a Eureka moment, isn't it? When you've had a patient who's really ill, and there's nothing else you can do and the patient isn't getting any better. And then discovering, LDN could possibly work and seeing what the results are. I find it really fascinating. 

Dr Eric Borgeson: It is fascinating and satisfying.

It's at that moment that you're able to feel like ‘that's where we got into medicine’, to help them out with these things, to make it, to give them the treatment that they need to help improve the lives that they have. 

Linda Elsegood: You said that you compound supplements as well. What would your recommendations be to patients who take LDN? What supplements would you say they should be taking or checking?  

Dr Eric Borgeson: Yes, because a lot of that's what attracts them to help with the inflammatory disorders. We usually recommend other anti-inflammatories to go with it.

Or perhaps B12. Or other complexes that we have, just an overall energy-boosting for our patients who have chronic fatigue syndrome, or it may be that we also recommend they get their iron levels tested to make sure that not just a vitamin D issue, that it actually sees if there's any iron component to it, that's missing, that they don't have enough steroids and things like that.

Linda Elsegood: Why would somebody have low iron if they had a healthy diet? 

Dr Eric Borgeson: They may not be getting enough iron from their natural diet. Over here in the States, we have a lot of vegans or vegetarians that if they don't get enough beans or other source of iron or even just iron supplements taken with something such as citric acid or even just orange juice with it.

They may actually get enough absorption, and they might not be getting enough just in their diets as I said, from lack of iron sources. It's like they're not getting enough iron from beans or things like that. 

Linda Elsegood: How would you know if your absorption was working correctly? 

Dr Eric Borgeson: You'd have to get a lab test from your doctor and then get a blood draw to see what the levels were and then take them, they do move slowly.

So you'd have to draw blood, with a retest after six to eight weeks to see if you were deficient. I had to get our tests in six, eight weeks to see if the levels are brought up or not. And then you can slowly continue to supplement from there. For example, my own baby, at 18 months, was getting a great diet and drank milk.

He did everything, but he still had an iron deficiency, which was surprising to us when we brought him to the doctor. So we give him a vitamin supplement, iron supplementation for three months or so, and now his iron levels are up to normal and up to date, and we've been able to stop the supplementation.  He's able to maintain his iron. 

Linda Elsegood: That's good. So you don't necessarily need to take it for life just to increase it. 

Dr Eric Borgeson: Well, no, that's good just to correct it.

Linda Elsegood: Yes. Okay. So when a patient comes to see you, I mean, obviously you're not prescribers, but if you notice there was something that could help a patient, how would you go about informing them?

Dr Eric Borgeson: If we see a deficiency that we can help with a patient, we'll write them up in a note and tell everything. Like, this is what we recommended to your doctor. And then we ask if they want us to fax it over to them on their behalf or if they want to bring it into their doctor or they want to call their doctor about it.

So we'd help educate them about what the issue is, why we think this is a good treatment for them. Why is it a good way to progress? Then for them, with the way to get what we suggest that they should get. Most prescribers in our area have worked with their patients for years, or decades even.

So anything that a patient brings to them, they're mostly willing, they're most likely to let them try it because it has a sound rationale behind it that's opposed to, you know, a patient saying, Hey, I found something on the internet. Great. 

Linda Elsegood: And what do you think the response would be if you suggested LDN for these chronic fatigue patients or MS patients.  Do you think the doctors would be open to that, those who haven't previously prescribed? 

Dr Eric Borgeson: I do think it happens with doctors who have previously prescribed it. Some may be sceptical about it at the beginning, but then they just want what's best for their patient. So if they don't have any negative experiences, they will invest my track record in my history.

In nineteen years, I'd never actually seen any really severe allergic reactions. And they don’t see any severe adverse effects from taking low dose naltrexone. All I've seen is that's what's happening with someone who was on opiates before and got a medium dose of naltrexone and they now went into withdrawal a little bit.

But that was the only a slight case of anyone who's had an adverse reaction from our experience with it. So most doctors in that instance, when presented with a lot of positives that can occur from it and not a lot of negatives, then they're more willing to prescribe it for their patients.  

Linda Elsegood: What would you say the outcome has been from the patients that have tried LDN?

Dr Eric Borgeson: I can say it's not all of our patients, unfortunately, that get benefits from it. It seems to really be about six out of 10 or seven out of 10 patients who do take it and take it regularly and as they're taking it at bedtime, take it roughly the same time, at bedtime. It seemed to have the best effects with it, but as not all medicines work the exact same way for everybody, it doesn’t work for everyone, unfortunately.  

Linda Elsegood: What dose range do you compound? 

Dr Eric Borgeson: The majority of our patients, we have a total range. Once we have to do one and a half; we have two-point ones, three ones, three and a half, four and a half. We have a few patients on six points, and we've done a few patients up to nine.

But the majority are down in the three and four and a half range. Because most of the studies in LDN, most of the tests and most of the studies have been done on the four and a half milligram variety of low dose naltrexone as opposed to higher doses. And then we start the lower doses because people should be titrated up slowly as opposed to just jumping to the highest dose.

Linda Elsegood: And what I was saying about pain specialists is because pain specialists now are using ultra-low dose LDN, which is 0.001 so it's, you know, really micro-dosing, and it seems to work absolutely amazingly by using this microdose alongside the opioids, not taking them off, keeping them on makes the opioids far more effective.

And then they're able to decrease the opioids while increasing the microdose, and in some cases actually weaning people off the opioids, some that have been on opioids even 20 years. I heard a story the other day about coming off the opioids on LDN and having better pain relief than they were on this cocktail of opioids and didn't go through withdrawal.

Dr Eric Borgeson: Now that is just amazing. 

Linda Elsegood: Yeah. We're doing a documentary on opioids and LDN, and we've interviewed several pain specialists who have amazing things to say, so we are hoping for big things with LDN, and hopefully, we will have to get you to make ultra-low-dose as well. 

Dr Eric Borgeson: Excellent. Well, we look forward to that.

We ought to have more papers on that? 

Linda Elsegood: Yes. 

Dr Eric Borgeson: So I thought they had talked about micro dosing and nano dosing. The question is more homoeopathic sometimes at that point where it's like, what? How small of a concentration can you have before you actually start to see an effect? That'd be fantastic.

That doesn't have to be that high, and it doesn't cause any withdrawal effects on you simultaneously. Improve anti-inflammatory at the same time, not have to use such high doses of opiates. 

Linda Elsegood: Exactly. And the pain specialists that do use LDN at 1.5, will use it with opioids, but only several hours apart.

So if you take one in the morning, you take the other one at night. We don't ever recommend that. Nobody does that themselves, that always has to be under medical supervision, but there are doctors that will do that and find that it does work really well, but maybe it's the same thing as the ultra-low dose alongside the opioid making it that much more effective, but it's certainly something that is a hot topic at the moment. Which is really interesting. So what's your next goal in your pharmacy? 

Dr Eric Borgeson: Our next goal? So, currently, we are rolling out our USP 100. We're working with the regulation part of that to improve us. And then we also have some creams out for testing now to help increase the bud study, like the beyond use stating that people can have for pregnant alone.

Cause right now there are no studies that pregnenolone is only good for 30 days based on U of T seven, nine, five. So we've put some out to a testing lab when we're on day 90. Now. We've had good results so far. Um, so we're pushing the boundaries there on science to see how long, um, we can get pregnant alone in this space for so that patients can, you know, have larger day supplies and less frequent turnover of medication, like having to order it and decreasing the burden on them.

Linda Elsegood: So what, what is that actually for? 

Dr Eric Borgeson: Oh, pregnant. It's part of 'em. Uh, the hormone. a homeowner placed on therapy greens and helped synthesize other hormones for you. That's like a precursor. 

Linda Elsegood: So when people take hormone replacement medication, I mean. Is that just one medication once a day or do they have to take more?

Dr Eric Borgeson: Some prescribers use it once a day, and then some prescribers do it twice a day. It depends on the doctrine—the prescriber.

Some doctors want to keep the levels up more sustained and found that trees, it's the cream today seems to be more effective than once a day. So, again, that goes back to being patient dependent as some of their patients only use them once a day, and they seem perfectly happy with it. And sometimes it's just replacing progesterone that we've, that women lose over time, like people who are over 50, maybe experienced progesterone loss.

So then it's just bringing their progesterone levels back up to where they were normally originally. Um, so we're just, then at that point, you're just supplementing the progesterone at bedtime, and that's it. Cause it can cause drowsiness and some people as well. So, um, you wouldn't let me drive there during the day.

So the prescribers prescribing more. 

Linda Elsegood: And what about, um, blood tests? Do they always come back showing that they're, the tests are negative or positive even for thyroid problems, hormone problems? What I'm trying to ask is, is it a, is it a clear cut thing where, you know, this is the marker you've got, so you definitely need some help or, or are the grey areas.

Dr Eric Borgeson: I would say there's a grey area. There are black and grey areas where it's like, while you're, it depends on what level they're looking for. Like people who are high roid. Some people just look at the thyroid-stimulating hormone levels and base it off of that when they should really be using more of a direct T three and T four, um, blood tests.

It's a little bit more expensive obviously, but they use the direct T three and T four just to ensure that your body is converting. The T four into the active teeth three and then back to the inactive T four. And if it's not getting to the active state, then it looks fine on your blood work on just a thyroid-stimulating hormone side.

Ella is finding your blood work, so then it won't be fine. Um, once they, once you take the direct levels. 

Linda Elsegood: Hmm. Because I know, I know some people have had tests gone to one doctor and had the tests and been told the fine, then go to another doctor would have a different test and find they actually do need help.

Dr Eric Borgeson: I'm really alone in college where I was like, are you treating the numbers or you're treating the pain. And so they would be looking at the symptoms that the patient's experience in regards to, you know, are they losing weight? Are they having excessive sweating or, you know, are they just gaining weight.

The irritable or you somnolent infant, you know, are they, are they too tired? Not tired enough, too much energy, not enough energy. There are so many variations, professor, for the thyroid patients that they have to take into consideration, 

Linda Elsegood: but it's not helpful. Is it? When you go to the doctor in the field.

Really unwell to be told that your blood tests are normal. There's no further action that needs taking, you know, but hang on, I don't feel very well. There is something wrong with me. And then, of course, some of these patients are then told it's all in your head, you know, that you imagine it. 

Dr Eric Borgeson: Yeah, there's that. Unfortunately, that does occur. Um, but yeah, I look, people always want to go, you got the people who don't even want to go to their doctors, but then they're like, well, I need an answer. I need to know what is wrong. And then after going their doctor, they're like, my doctor said there's nothing wrong and enough must not be anything wrong.

Linda Elsegood: So what, what are you going to say? What are you able to do as a pharmacist? If a patient comes to you and says, ah, I've had these blood tests, and they're all negative. There's nothing wrong with me yet. I'm really not. Well, how do you help those patients? 

Dr Eric Borgeson: We interview the patient at that point. Part of that is not feeling well and then try to find what may have paused that from the start, like more of the history and the biography of what caused their own wellness and then what things they've tried to further on wellness.

And then either possibly recommend a different doctor for them if they didn't go with a doctor who specializes in what seems to be wrong with them. Um, or maybe we've had to do tiny on what they say. We might have to do some further research. With them to see what else we can find on their topic of what seems to be ailing them.

What are things that we may not have even considered? 

Linda Elsegood: Yes. Yeah. Now, as I say, you're in New Jersey, so how far, you know, if you look at the whole state of New Jersey, whereabouts are you based? 

Dr Eric Borgeson: What about in the middle? Against the shore. We're, we're an hour and 15 minutes South of New York City, about an hour north of Atlantic City and an hour and 15 minutes diagonal from Philadelphia.

So we're ready against the shore about halfway up 

Linda Elsegood: on the coast. Okay. Yeah. I've actually been to Atlantic City as well. I, I came back, and I think I was home about a week and they had those terrible storms or hurricane or something and it ripped all the boardwalk up, but it was quite nice. I was saying to my family; I went here. I went there.

It didn't look like that, though. Um, I think I would have been, yeah. Quite frightened if I'd been there when that happened, but I did 

Dr Eric Borgeson: see it. Hurricane Sandy was not a nice hurricane. I had lost power for a day or two. There are people that have the pharmacy. I worked at the time. It didn't have power for a week.

Wow. You know, it was very, very traumatic. That was even in that, in inland, like 10 miles, like 10 15 miles. Like it was a very. Like for all the trees and knocked down and all the damage it did. It wasn't just the ravaging shoreline, which it did that as well. Burying houses and just strolling the entire, every house on the Island pretty much was almost seemed to be knocked down at some point.

Linda Elsegood: Goodness, 

Dr Eric Borgeson: there's so much damage on the Island, 

Linda Elsegood: but wow. 

Dr Eric Borgeson: I mean, we rebuild them. It's better than it was before, 

Linda Elsegood: but you do have more extreme weather them than we have here. 

Dr Eric Borgeson: Occasionally there's not, you know, that's, I've only had one hurricane since I've been here, and that's the one. 

Linda Elsegood: Okay, well, that's not so bad.

That isn't 

Dr Eric Borgeson: it. Did you get some torrential downpours? Do get some lightning and thunder. They are always borne up tornadoes, but no ones. I'd never seen one in this area.

Linda Elsegood: but your position, um, how you will be located. You know, what area do you cover around your pharmacy? How far do people travel?  

Dr Eric Borgeson: ah, people can keep seeing how people travel up to 45 minutes to come to us. But we do mail like we ship prescriptions. Um, we just compounded prescriptions. We do ship for free throughout the state.

Because we're licensed in all States, so we'll have the doctor, well, doctors will fax over their prescriptions, or they'll call them in, and then we'll get them ready, and then we send them out to the patient, so they don't have to make them if they're over 45 minutes away, they don't have to travel there to get their prescription if they can't get anywhere else.

Linda Elsegood: And your license in which States did you 

Dr Eric Borgeson: say it's in New Jersey where we are, but we're licensed in eight States, I believe. 

Linda Elsegood: Okay. 

Dr Eric Borgeson: We're licensed in Arizona, Connecticut, Colorado, Ohio, Pennsylvania, New York, Florida, Maryland. Those are the ones that come to mind 

Linda Elsegood: for pushing you on the spotlight. It's a tricky, tricky to remember, isn't it? Wow. So do you think, um, Philadelphia, didn't you say you near Philadelphia? What was it about Philadelphia? Do you ship there, Pennsylvania? 

Dr Eric Borgeson: Yes. We do ship to Pennsylvania. There's a children's hospital on the edge of Pennsylvania that we do a lot of compounds for. There's a children's hospital, Philadelphia, and we help take care of some of their patients. 

Linda Elsegood: Oh, okay. Wow. We've just about come to an end.

Um, you've already given your contact details, and that will be on the video for people to see. So thank you very much for having been my guest today. 

Dr Eric Borgeson: Thank you very much for having me. I look forward to seeing you guys may come to visit New Jersey. 

Linda Elsegood: Thank you.

Jersey Shore Pharmacy is a fully licensed and accredited pharmacy in New Jersey, specializing in compounding formulations. Such as LDN, bioidentical, hormone creams, home appraisal, and pet medications. They strive to help everyone with their individual needs. Visit https://www.jerseyshore.pharmacy/  or call 01 (609) 660-1111 Monday to Friday 9:00 AM until 7:00 PM. Saturdays. 9:00 AM till 3:00 PM.  You can also find them on Facebook. Today I'd like to welcome my guest pharmacist, Eric, Borgeson from Jersey Shore Pharmacy in New Jersey. 

Any questions or comments? You may have. Please email me at contact@ldnresearchtrust.org. I look forward to hearing from you. Thank you for joining us today. We really appreciated your company. Until next time, stay safe and keep well.

keep well.

Dr Tom O’Bryan, LDN Radio Show 12 July 2017 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr Tom O'Bryan shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Wheat sensitivity can cause an immune response, not just gluten. Hydrochloric acid in the stomach breaks down the proteins and enzymes in the gut convert them to amino acids, which permeate the intestines and enter the bloodstream. Wheat causes increased intestinal permeability ("leaky gut") in everyone, but not everyone suffers from eating wheat because wheat is a minor irritant. At some point, symptoms of intestinal permeability are likely to appear due to loss of oral tolerance, and can result in various autoimmune disorders, such as Hashimoto's. Reducing dietary wheat can arrest the development of autoimmune disorders. A wheat-free diet is easier to follow when patients understand that inflammation can be reduced by following the diet. His book, The Autoimmune Fix, has recipes. For example, take 1 Tbsp chia seeds, which are high in Omega 3s, stir into coconut milk till it starts to gel, refrigerate, add crushed fruit, and you get a healthy dessert.

Dr Tom O’Bryan, LDN Radio Show 01 Feb 2017 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr Tom O’Bryan shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Dr Tom O’Bryan is the founder of www.thedoctor.com and is an internationally recognized speaker and workshop leader specializing in non-celiac gluten sensitivity and celiac disease. He hosted the gluten summit, and stars in the documentary series, betrayal, featuring the autoimmune solutions. He’s also written a book called ‘The Autoimmune Fix’.

In this interview Dr O’Bryan explains his many years of analysis in terms of the effect our diet can have upon our immune systems and subsequent immune responses we have to autoimmune diseases. The over-consumption of products such as milk, wheat and dairy in general can be damaging and our diets must be moderated.

This is a summary of Dr Tom O’Bryan’s interview. Please listen to the rest of Dr O’Bryan’s story by clicking on the video above.

Dr Thomas Cowan, LDN Radio Show 14 Dec 2016 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr Thomas Cowan shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Dr Thomas Cowan practices holistic medicine in San Francisco and prescribes Low Dose Naltrexone (LDN). He also has a new book called ‘Human Heart, Cosmic Heart’.

He first heard of LDN in 1992 from one of his patients with AIDS who requested it. This occurred again four years later, prompting Dr Cowan into researching LDN more thoroughly and learning about its many benefits in combating autoimmune diseases.

He says that LDN’s side effects are very uncommon and that in 95% of his autoimmune patients, he has prescribed LDN. Dr Cowan is a strong advocate of LDN.

This is a summary of Dr Thomas Cowan’s interview. Please listen to the rest of Dr Cowan’s interview by clicking on the video above.

Dr Thomas Cowan, LDN Radio Show (LDN, low dose naltrexone) from LDN Research Trust on Vimeo

Dr Thomas Cowan shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Dr Thomas Cowan first came across Low Dose Naltrexone (LDN) around 20 years ago when one of his close friends had incurable lymphoma. Having refused to continue on conventional treatment which had little to no effect on improving his health, he researched alternative treatments and came across LDN which drastically helped him to recover.

In the last decade of his career, Dr Cowan has predominantly treated patients with Ulcerative Colitis (UC) and Crohn’s Disease, finding that LDN can be successful in treating both diseases and providing great relief to his patients.

This is a summary of Dr Thomas Cowan’s interview. Please listen to the rest of Dr Cowan’s story by clicking on the video above.

Nurse Practitioner Seth Merritt, LDN Radio Show (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Seth Merrit, LMT, FNP, CATOM, CLS

shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Seth Merritt is a nurse practitioner from Portland, Oregon who prescribes Low Dose Naltrexone (LDN). He himself takes LDN for psoriasis and has a great deal of success.

Having witnessed his own recovery on LDN, he was determined to ensure that others do not miss out on the opportunity to try the drug. 

In this interview he explains how he finds LDN to be very successful in treating many of his patients with fibromyalgia.

This is a summary of Seth Merritt’s interview. Please listen to the rest of Seth’s story by clicking on the video above.

Dr Scott Zashin, LDN Radio Show 2017 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr Scott Zashin shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Doctor Zashin from Dallas, Texas, is a Rheumatologist who is Board Certified in Internal Medicine. 20 years ago he changed his practice to specialize in autoimmune conditions which required more time to evaluate and treat. 

Unlike most Doctors who allow only 10 to 15 minutes per visit, he spends an hour or more as necessary to get a firm grasp of the patient's problems. He discusses the many autoimmune conditions he treats and how LDN fits in, and why diet and exercise are very important.

This is a summary of Dr Scott Zashin’s interview. Please listen to the rest of Dr Zashin’s story by clicking on the video above.

Dr Sally Boyd Daughtrey, LDN Radio Show 2016 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Linda Elsegood: This evening. I'm joined by Dr. Sally Boyd Daughtrey, who's a licensed naturopathic doctor from Hawaii. Thank you for joining us. 

Dr Sally Boyd Daughtrey: Aloha. Thank you for having me. This is a great opportunity to share my experience with naltrexone. 

Linda Elsegood: Could you tell me when you first heard about LDN? 

Dr Sally Boyd Daughtrey: Well, this is a very interesting question, because it just sort of - I don't know if you know the word grok, but it just sort of grokked towards me from the universe and just different layers. There's not a particular time that I went, Oh wow, naltrexone is amazing. It just sort of became clear to me. But the first time I prescribed it for a patient, it's something I will never forget. It was astonishing. I'm sitting in my office, and I hear this banging on the wall of my waiting room, just this thump, thump, thump; and my receptionist was at lunch. So I was alone; what is that? So I am flying out to the waiting room, and there's this lovely waifish ill woman laying on the floor of my waiting room, and she was trying to drag herself through the waiting room to get to the reception desk by banging, by grabbing a wall, literally dragging herself through the waiting room; and it was amazing. So I reached out and I picked her up, and I put her in a chair, and I took her in the back and started doing her interview. She was an MS patient who had been through everything and couldn't walk because of the MS, and had no money, low-income, literally stumbled into my office off the street. There was very little I could do for her because I do private medicine, I don't take insurance. But I remembered naltrexone. Someone had told me about this thing called naltrexone. This is about 2007, 2008. I managed to find a compounding pharmacist that knew what the heck it was and prescribed it for her. And within two weeks she walked into my office. Two weeks, and all I had done for her was naltrexone and some vitamin D, because that's all she could afford. I saw her for two years when she could come in and see me. She had no relapses. One more thing we did, I gave her a grounding mat. I don't know if you know what those are. It's just a very simple device that helps connect you to everything, helps you connect to the earth and reduce EMF exposure, basically.

So those were the only things that we really did. And in those two years, she had no relapses at all. And I know people say, Oh, well, MS has spontaneous relapses, but really come on, the chance of that happening was so low. And the only reason I lost track of her is that she got well enough to get married and moved to a different state. So that was the pretty astonishing start and my exposure to naltrexone.

Linda Elsegood: So where did you go from there? 

Dr Sally Boyd Daughtrey: As you can imagine, I was pretty impressed, so I started using it specifically for autoimmune conditions at first. But as you know, autoimmune conditions are epidemic everywhere, and the more you look for autoimmune conditions in a wide variety of symptoms, the more you find them. So I started going with a lot of my Hashimoto's patients next. And it's sort of becoming my go-to if someone has thyroid symptoms; there are hundreds of thyroid symptoms. I have a thyroid questionnaire that's 2-3 pages long, with symptoms and overlapping with other conditions, symptoms, and whatnot. If someone shows a lot of thyroid symptoms I run antibody tests on them, and if they're high at all, then it's pretty much an automatic thing now that I put them on naltrexone. And what I love about running antibodies is because, especially with thyroid patients, you can get a baseline antibody level, and you can put them on the naltrexone, and you can watch that number drop like a rock. I had one person come in with 1200 antibodies, and three months later, they're something like 30 to 60. That's not uncommon, to have those antibodies go down that fast. And ANA and anti-TPO and TBG are well-accepted tests.

And it's a good thing to actually have something they can take to their MDs, who tend to be more in the medical establishment. So there's good about that and bad about that. One of the bad things about being in that system is if you're entrenched in that system, it's harder, there are more social stigma and financial stigma for them to break free of that dogma. So it's really refreshing for me to be able to say, here are the baseline autoantibodies when my patient walked in the door, and here are their antibodies ten times lower three months later, what do you think of that? And the more forward-looking of these that my patients also see, because most of my patients see an MD as well because their insurance covers it now - I use that as an educational tool for, for them to help increase exposure to this treatment. 

Linda Elsegood: So, do you have any other stories? 

Dr Sally Boyd Daughtrey: I can tell you my own story. I've had Hashimoto's thyroiditis for 25 years. I got it in medical school and I remember the reason for getting it, in my mind, was cadaver lab, being exposed to huge, massive amounts of formaldehyde in a high-stress environment, and then autoantibodies started going up from there.

And it was presented to me, even as a naturopath where we treat a lot of things outside the box that isn't supposed to be treatable; even in that context, it was presented as well, we can manage this, but you're always going to have gluten sensitivity and weight problems and fatigue, and we'll check your autoantibodies every now and then, but there's no need to really redo them again because now we know you have this disease and it's not treatable.

So basically the plan that was presented to me - I'm in my early twenties - was here, they'll give me this thyroid medication, and when it stops working, we'll give you more. And then when it stops working, we'll give you more. And then when you reach the max, we'll just keep you on that. And good luck with that. And you think, okay, I'm swimming against the stream by becoming a naturopath, so the things that aren't treatable are supposed to be treatable with our medicine. And you're telling me that this is not treatable, or it's something super elusive like - maybe it's your mercury exposure or something like that. And then 20 years later, take one little pill at bedtime and have that condition dramatically improve, it was amazing. And to be able to actually track that on lab work, and say it's not just me, it's not a placebo effect. I can't really see how a placebo effect would reduce an autoantibody level on a lab consistently. Yes it could take a little bit, but that's obviously not all that's going on here. 

So myself starting to take it resulted in my being able to go from a part-time practice to manage my condition, to a full-time treatment centre. So now I have staff, and I have ancillary services, I have an associative MD, and I have all these things that I'm able to manage now because that condition is successfully - I wouldn't say cured because to me cured means you don't need to take anything to not have your symptoms. So I would say that naltrexone has created the ability for me with a wide range of conditions to successfully manage them, and moderate or eliminate the symptoms. 

I would say maybe 20-30% of my patients that come into this clinic get naltrexone treatment. Part of that's a reflection of the fact that I treat recalcitrant patients in the first place, meaning I treat patients that have pretty much been through regular medical care and have not been fully resolved with that or satisfied with that. So that population is somewhat self-selected to be a more difficult treatment population in the first place, and that's part of what naturopaths tend to do in this country. When you have a success rate that is high with a population that already has failed conventional treatment, you know you're doing really well. It's a very gratifying profession in that way.

I would say it's an appropriate fit for about a third of my patients. Of those patients, about 60 to 80% stay on the therapy and self-refer themselves to stay on it. Meaning I'm not sitting there wondering how to track compliance. They're calling in to get their prescription refilled. They're choosing to stay on it because they perceive that they feel better when they're on it, and that's pretty quick too. 

I'm reading the LDN Research Trust website, which is super useful by the way, this is a great website, and there are all kinds of things on there that I didn't know, that's useful. I've been expecting people to have a significant symptom change within two weeks, and then I'm reading on here that a lot of the chronic pain patients can take three months to have a significant benefit. So I am able to condition people to wait that long to see a benefit. And still I'm seeing 60 to 80% of people staying on it and reporting improvement.

Part of that might be me encouraging them to notice an improvement is having a positive mental effect for sure. Everyone that comes here is paying cash to see me and is paying cash for the therapies because insurance doesn't cover what I can do. So if you're going to keep paying for something, you definitely perceive a benefit from it. 

Linda Elsegood:  On the flip side, has anybody told you that they experienced any negative side effects? 

Dr Sally Boyd Daughtrey: Well, the sleep change, sleep disturbance, insomnia effect is definitely a factor. And for that, I would say maybe 20-30% of people will report that. There are some people of course that come here, see me once to try something and then I don't see them again. I don't know what happened to them. They don't follow up. It's not the right kind of care for them. So I can't say what those people are doing if they have the insomnia effect or not. But people that come in and are consistent and do the therapy, it seems to me like there's a certain subset of patients that have that symptom. I haven't quite pinned down who they are, except that they tend to be more sensitive and more anxiety-prone, more reactive. I do see a lot of chemically sensitive people, canary in the coal mine kind of people, and  their dose-response rate is very individual. So I have people on 0.5 milligrams and I have people on 12 milligrams. That's a huge range, and I've come to that with people through very specific trial and error. 

A lot of my patients are very intelligent too, they're very motivated and follow instructions well, and can do some self experimenting. Which is a wonderful thing about being a naturopath too, that that population kind of seeks you out. So I'll start them on say one milligram for a week and then have them try 1.5 and then try 2, and change the dose, and keep a log and ask, how did I sleep last night? Did I have vivid dreams? Were they pleasant or unpleasant? Were they disturbing? A lot of autoimmune people have disturbed sleep, so they're not used to dreaming at all, or they're not used to remembering their dreams. So they find that startling at first. But then if you take the time to inquire and ask if it was a bad experience, they say no, actually it was a good dream. Well, maybe that's okay. That's not a bad thing. So part of it's how you see it, but definitely, people will have restless or disturbed sleep the first few nights, but I haven't usually found it to last more than three nights. 

What I do now just for simplicity sake is to start them on, let's say three milligrams, but the first night I'll have them open that capsule and pour nearly all of it out. And then the next night I'll have them pour all but a quarter out, and then stay on that for about three nights. And once they're sleeping through the night, then I'll slowly start adding back a quarter of the capsule at a time until they're taking the whole three milligrams without any problems. And that works 99% of the time.

Linda Elsegood: I would say that there are many doctors that actually swapped to morning dosing for people who find sleep is an issue. And it seems to work just as well in the morning. 

Dr Sally Boyd Daughtrey: And they're not noticing any downwards depressions spike at any time after taking it? 

Linda Elsegood: No. And there are some people who have been taking it in the morning, swapped to the evening and feel that actually taking it in the mornings they have less fatigue. I take it for MS, and I've swapped from night to morning and it didn't make any difference. And there are some doctors that prescribe LDN for chronic fatigue syndrome, double dosing, so the dose that they take in the morning they take in the evening as well because the body doesn't see it as double. So if you were taking 4.5, the body doesn't see it as nine, it sees it as 4.5 twice, because at the time you take the second dose, the first dose has been gone. I tried that as well. That didn't give me any more energy either, but I at least gave it a go.

Dr Sally Boyd Daughtrey: That's a really great idea. And I actually just had someone who just on his own decision, started taking it in the afternoon because he was afraid. We have lava here, this volcano that tends to threaten to cover the town every now and then. So he has severe anxiety and he lays awake at night and worries about the lava covering his farm, which I can't say is an unrealistic worry. So he started taking it in the afternoon and reported an immediate improvement in mood within 20 minutes. And thinking about the path of how it's supposed to work in the body, I don't understand how exactly that's happening, but I can't discount this experience. It's a consistent experience and who am I to say to stop doing that, you're doing it wrong; because for him, it's right. So I just put him on doing it in the afternoon and then trying a very small dose in the evening to see if it helps. 

And the wonderful thing about this stuff is that at these doses, it seems so safe that allowing people to experiment with it and find what works best for them, and then tracking their results and making sure that their lab work is in order and they’re progressing in all aspects. I do regular physicals and I can see people's physical parameters improving.

I don't do just naltrexone. In this kind of setting, I'm doing naltrexone and nutrition changes and counselling and lifestyle modification, and I'm doing all of these things together, and it doesn't really serve my patients to just do one thing so we can test it. Now that's a very difficult sell, right? So that's the whole problem with holistic medicine, with testing holistic medicine in general, that it's the sum of its parts and it's a synergistic sum of the parts. So if you try to reduce that down to what's just naltrexone effect versus what's this lovely whole food B-vitamin that I've switched to them too, and taking them off their synthetic kind that was causing anxiety, for example. 

That's challenging for the standard medical paradigm to accept as a real therapy. I don't really know what to do with that, except to compare people that get that holistic treatment with it with people who choose not to have naltrexone because some of my patients are against all pharmaceuticals. I have a subset of the population who are seventh day Adventists or Amish or someone like that. And they will not do a conventional pharmaceutical of any kind. Even this one, even this very benign one. So the only way in my mind, can ever really extract what naltrexone is doing individually is to compare the progress of those people in general, with those other people who do all of that plus naltrexone. I've been doing that admittedly in my own head, keeping a tally in my head, since 2007 or 2008, so that's 30 years, and a lot of people. My overall very strong impression is that the people that do everything plus naltrexone do significantly better than the people that choose not to do it for whatever reason they're choosing not to do it.

Linda Elsegood: And if we have people listening to you in Hawaii and they'd like to come and see you, how did they contact you? 

Dr Sally Boyd Daughtrey: Our practice is called Vitality Integrative Medicine, and we are a comprehensive integrative clinic in Pahoa, Hawaii. Our phone number is 808-965-2233. Our website is http://www.vitalitymedicine.org/

Linda Elsegood: Is there anything else you'd like to add before we finish? 

Dr Sally Boyd Daughtrey: I guess one thing that I'm thinking of doing now is expanding who qualifies for this therapy. What are other doctors finding results with this that are beyond cancer, autoimmune, pain syndrome? That's something that I'm really interested in because it seems like... 

Oh, PANDAS, I had an amazing PANDAS. It's a cross - one of the things that we're seeing more and more now is cross-reactivity is in the human body to past infection. So someone who's had an infection in their childhood, say strep, or staph, or Lyme; then their body will mistake the antibody for that bacteria to a piece of their own body, their own tissue, and then they will have chronic problems with that particular organ. I'm having some really interesting results with people like that. They don't even always know that they have an autoimmune condition. They feel like they have a heart condition or a skin condition; or in this case, a mental, emotional psychosis condition. And naltrexone seems to be helping - kind of in layman's terms, it's helping the immune system be happier and calm down, and recognize what’s a friend and what's foe more accurately. The implications of that are huge.

Linda Elsegood: At the conference in February, we had two psychologists talking about post-traumatic stress. But it seems to work for cravings and all sorts of problems that people have. So the more we are using it, the more conditions are coming along that doctors are treating with it. We now have a list of I think 204. Normally, if there's an altered immune component, LDN could well work; and then there are all the different pain conditions, there are these mental health issues that it's helping with as well. So it's very interesting. We're learning all the time. 

Dr Sally Boyd Daughtrey: One that I also am treating for - I don't have a large population of people partially because they're self-reporting is poor, there are some shame-based issues with the self-reporting, but the euphoric drugs of abuse like ecstasy and Molly and MDNA. Those kinds of drugs. I think people that use those and use them and use them and use them, end up depleting not only dopamine but endorphin and enkephalin as well. They tend to present with this sort of chronic low-grade apathy, dysthymia, hopelessness, lassitude. The only thing that seems to make them happy is when they're actually on that drug. So, although it's not technically “an addiction or an addictive drug” by classification, their life ends up being cycled around the use of that drug. When I can get them to take naltrexone and stop taking that drug of choice, it seems to make them feel normal. And it makes me feel hope for these people because they're self-medicating in a way. If their endorphins are chronically low and they don't know that, but they know that they get to actually have an experience of having normal or high endorphin levels for a few hours, you can see how their life would then end up revolving around wanting that feeling of actually feeling normal. Here we are saying for the first time in your life, you can feel good, not high, but good every day. And that can be your baseline reality from now on. That's incredibly powerful. That's a life-changing experience. 

I've had a couple of patients who have been able to tell me this is the cycle they’re stuck in, and I've been able to say, well, if you can commit to weaning off that drug, not doing it every three nights or every week and/or living for it, and instead, do this because I would think that they would contradict. So I don't want them doing naltrexone and that drug at the same time; I don't know what that would do. So then we actually make a contract: you do naltrexone. If you want to keep doing your illegal drug of choice, don't do naltrexone that day, please. And they find that they need that drug, whatever their drug is, less and less. So that's very successful; that's very satisfying.

Linda Elsegood: Thank you very much for sharing your experience with us. 

 

Any questions or comments you may have, please contact us.  I look forward to hearing from you. Thank you for joining us today. We really appreciated your company. Until next time, stay safe and keep well.

Dr Ronald Hoffman Interviews Linda Elsegood on LDN and The LDN Book (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Linda Elsegood shares her Multiple Sclerosis (MS) and Low Dose Naltrexone (LDN) Story on the Intelligent Medicine Podcast with Donald Hoffman.

In 1969 at the age of 13, Linda had glandular fever (Epstein-Barr virus). She was seriously ill and away from school for six months. 

Late 1999 Linda’s mother had a serious heart attack and the trauma affected her badly. She was working full time, travelling two and a half hours every day and running the home. This excessive workload and stress began to take its toll on her health, and by May 2000 she had lost her balance, lost feeling in the left side of her face and her head, tongue and nose were numb with pins and needles.

In early December 2003 Linda started Low Dose Naltrexone (LDN), and the results were incredibly positive. By Christmas Linda was functioning again, and her liver tests were back to normal. She felt like herself again.

Linda founded the LDN Research Trust in May 2004. In this interview she says that it is the most exciting thing she has ever done. She is able to give many hours a week to the Trust, helping people to get LDN and trying to get it into clinical trials.

This is a summary of Linda Elsegood’s interview. Please listen to the rest of Linda’s story by clicking on the video above.

Dr Richard Nahas, LDN Radio Show 2016 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr Richard Nahas shares their Low Dose Naltrexone (LDN)

Dr Richard Nahas is an LDN prescriber from Ottawa in Canada specialising in Brain Function and Brain Health.

Dr Nahas practices in Ottawa, Canada at the Seekers Centre. He was an ER doctor for 5 years and in 2004 was involved in dealing with the SARS outbreak. He traveled extensively to other countries to observe the varied medical systems. 

For the past 12 years he has specialized in brain function and brain health. He explains how he does functional brain assessments through QEEG tests combined with observations of other neuropathic complaints. 

He has utilized LDN for a decade, and describes the various ways brain and nerve damage affects our health. This interview touches on Chronic Regional Pain syndrome, Neuroplasticity, and pain thresholds. He explains how pain is related to sleep disorders, inflammation, mood, injuries and diseases.

This is a summary of Dr Richard Nahas’ interview. Please listen to the rest of Dr Nahas’ story by clicking on the video above.