LDN Video Interviews and Presentations

Radio Show interviews, and Presentations from the LDN 2013, 2014, 2016, 2017, 2018 and 2019 Conferences

They are also on our    Vimeo Channel    and    YouTube Channel

Dr Sajad Zalzala - 4th July 2018 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr Sajad Zalzala shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Dr Sajad Zalzala, commonly known as Dr Z, combines unique qualities of an experienced doctor passionate about disease prevention and longevity, and a serial entrepreneur. Sajad has been passionate about slowing down and reversing age-related diseases for 20 years. 

He decided to become a doctor after reading Ray Kurzweil’s books. He became interested in integrative and functional medicine as a medical student. He currently sits on the board of the International College of Integrative Medicine (ICIM).

For the last several years, he has run an online clinic dedicated to prescribing LDN to patients across the US and most of Canada and has treated over 1,000 patients with LDN.

This is a summary of Dr Sajad Zalzala’s interview. Please listen to the rest of Dr Z’s story by clicking on the video above.

Dr Michael Ruscio - 20th June 2018 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr Michael Ruscio is sharing his experience with Low dose Naltrexone.

He treats people suffering from symptoms like daily bloating, constant fatigue, and unexplained weight gain, simple steps to start living a healthy, enjoyable life.

There are many different conditions that I'm sure both clinicians and patients grapple with and it's hard to sometimes determine what do I do first.

Should I have a heavy metal test, an adrenal hormone test, a female or male hormone test, a thyroid analysis, a gut workup, a test for mold or Lyme? And I think a very prudent approach is to first start with your dietary and lifestyle foundations.

And there different diets that could be an appropriate starting position.

And then if they're not improved symptomatically I take steps to optimize their gut health.

And also along with that, I take a fairly cautious progressive look into the gut and thyroid health.

Oftentimes I'll start someone with a paleo diet and sometimes the paleo diet is typified to be this very high meat, especially high red meat, high-fat diet, but it really doesn't have to be. You can have a few different derivations on the paleo diet that can range all the way from high carb, lower fat to lower fat, higher carb.

But the main tenant of the paleo diet is the removal of process foods. And also a decrease consumption, if not elimination of things like most grains and also some beans and legumes and a focus on meats, nuts and seeds, fruits, and vegetables, and healthy sources of fats. And that's a really a good starting point for the gut.

Now, if someone comes in with a high degree of digestive symptoms like the classic IBS (Irritable Bowel Syndrome) type symptoms, gas, bloating, loose stools, diarrhoea, constipation, or potentially oscillation between the two then we'll oftentimes start with a low FODMAP diet, which has been very well studied in the context of IBS.

We could start with the standard low FODMAP diet that cuts out things that are not compliant with the paleo diet, like grains and dairy.

I think there are many clinicians who are moving this direction and kind of seeing this for most diets two to three weeks is enough time to evaluate. And you should have a sense that clearly you are feeling better. It's not to say you should feel 100% improved. Then keep going until you reach the peak of your best improvements and shortly after that, you can start to reintroduce some of the foods that you cut out, because for most people they don't need to adhere to the low FODMAP diet or the paleo diet 100%. They usually find that there are a number of foods that they can bring back into their diet and be okay with, but there's a few foods that have to be cautious with and when they reintroduce the foods, they have a reaction. So they can experiment and adapt

to a diet to themselves so they don't feel like they're being totally overcome by it by dietary restrictions.

One of the first things to consider is how many carbohydrates you're eating in your diet.

Usually, the lower someone goes in carbohydrate, the more fat they end up bringing into their diet because they need something to replace all of the carbohydrates that they've cut out. We have a high fat, low carb. Now some people with IBS do feel better when they eat a lower-fat diet, but there are also some people with IBS who feel better when they eat a lower carb, higher fat diet, almost like a ketogenic-type diet.

As to potentially have the risk of being too low carb for your metabolism and causing things like fatigue, insomnia, which can be a problem.  One of the things that people tend to do is bring back in carbs. We have people start with or more things like potatoes or sweet potatoes or squashes.

Some people are not incorporating enough healthy fish or fatty fish like salmon, sardines into the diet.

There is interesting research about thyroid and gut. That assessed, I think it was 1,809 patients. Being hypothyroid was the number one cause for small intestinal bacterial overgrowth or SIBO, which is a quite simply an overgrowth, too much bacteria in the small intestine. They also found that people with higher colonization of the Helicobacter pylori, which is a bacterium that can reside in the stomach connects back into the thyroid.

So it seems that the gut small intestinal, bacterial overgrowth, H pylori, hypothyroidism are all connected and by improving the health of one's gut, we can certainly see an improvement in thyroid autoimmunity.

Now, this is not published. This is more so what I've seen in the clinic, I think at some point we will see this published.

I would like to talk about the brain and gut health. I suffered from when I had gastrointestinal issues years and years ago. I was brain fog and brain fog is a terrible symptom. You feel like you can't hold a conversation because you can't remember things you feel kind of out of it. It's really an unpleasant symptom and there's research now being published showing the gut-brain connection.

The clinical literature says has found that for both anxiety and depression, probiotics have a favourable impact on both of these conditions.

And of course, probiotics can heal the gut in a number of ways. It can be anti-inflammatory, antibacterial and antifungal. So if someone has bacterial or fungal overgrowth, probiotics can help with those.

Diabetes is also amenable to dietary change. Type two diabetes that is typically one is a little bit more of a different story, but absolutely by improving one's diet, you can absolutely see fairly remarkable improvements in a lot of things.

I wrote a book "Healthy gut healthy. you". It's available on Amazon. You can also go to www.healthyguthealthyyoubook.com to learn more about the book.

But essentially this book was me trying to give people a very reasonable and responsible education on their gut health, why it's so important, all the things that they can benefit and then taking all that information.

Also, people can head over to my website, which is www.drrusso.com to book an appointment.

And I do see patients physically in my office in Northern California, outside of San Francisco, and also via telemedicine via Skype or what have you, if they're not in our area.

Summary of Dr Michael Ruscio interview. Watch the video for the full interview.

Dr AnnMarie Graziadio - 23rd May 2018 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr. AnnMarie Graziadio from New York, Apple Valley pharmacy shares her experience with Low Dose Naltrexone.

I got my bachelor's degree in pharmacy at Northeastern university in Boston. Right out after getting my bachelor's degree, I continued on to receive my doctorate degree in pharmacy from the university of Rhode Island. I did most of my clinical work at mass  general hospital in Boston. I then moved on and got a job for a pharmaceutical industry. Position at Solvay pharmaceuticals, which has now been purchased. I was coordinating clinical trials between that company and teaching hospitals, got to travel around the world and attend many conferences and it was fabulous.

Then I decided I wanted a family and I couldn't do that traveling three weeks out of the month. So I decided to go back into a clinical role at a hospital.

I ended up leaving Massachusetts and coming back to my home state of New York to be closer to family and raise my children here. I ended up getting a job with a local compounding pharmacist and when he was ready to retire, I purchased that pharmacy, which is now called Apple Valley pharmacy.

And we specialize in non sterile compounding. We service our local community where I grew up but we're also a bedroom community to Manhattan.

We're finding the patients that are using Low Dose Naltrexone have hardly any side effects at all and are just thrilled to find something that works that isn't interacting with anything or breaking the bank either when it comes to cost. They're a pleasure to work with.

Mostly, our LDN are capsules and we use micro crystal and cellulose as a filler.

A lot of our local providers start at 0.5 to one milligram and then slowly go up for 30 to 45 days to a maximum of 4.5 milligrams. But I honestly don't think I have anyone on 4.5 mg.

The feedback is great. There's no complaints at all. Obviously the titrating up is when they would normally say if they had any of those symptoms, like the vivid dreams and the nightmares, but we've had maybe one person say that they've experienced that during the titration phase and usually it goes away.

I usually ask them to call us within the first week of starting anything new, whether it's LDN or anything else that we would compound or dispense commercially.

We have a website which is www.applevalleypharmacy.com. We also have a Facebook page, which is also Facebook, Apple Valley pharmacy or patients can contact us via phone.

I can give you our number is (845) 988-5805 and we're readily available to help anyone that needs it. Our store hours are 9:00 AM to 7:00 PM. Monday through Friday. Saturdays we're open from 9:00 AM to 1:00 PM and Sundays we're closed and we ship our prescriptions that are compounded free of charge.

So if the person doesn't live in the immediate area, it's not a concern. We would mail it to them.

Summary of Dr. AnnMarie Graziadio from New York, Apple Valley pharmacy interview. Watch the YouTube video for the full interview.

Dr Leslie DeGasparis - 15th April 2018 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr Leslie DeGasparis from Seattle in Washington is sharing her experience with Low dose Naltrexone.

I'm an NDA naturopathic doctor. I went to the University of Washington for my undergraduate bachelor's degree. And then from there, I attended the Bastyr university for my doctorate in naturopathic medicine. And since then I've been practising for about 15 years. The first 10 were mostly primary care.

And then the last five I've concentrated on endocrinology with thyroid disorders and hormone balance.

Mostly, I attend women and I'm pretty happy with the outcomes of the infertility cases, especially when, on their last stop using LDN. They've usually already seen fertility doctors. And what I do notice is that something like LDN and really focusing on thyroid as well are often overlooked. So when we add those components to the fertility treatment, that pregnancy can happen.

Regarding LDN dosing times, historically over all these years, I've used it at night because originally that's what was said to work and it has worked. I'm a little wary dosing in the morning, but that being said for compliance reasons, in a few cases, I find that morning needs to be the time.

I'm watching these people to see if they do, as well as the models.

I have some people on doses between two and three milligrams longterm. We can watch their antibodies and we do know they're doing well. So I was very intrigued about the lower dosing and the intermittent dosing discussion in the conference this year.

I've had some pretty phenomenal results with some of the cases I have with children.

Children with autism in the practice where they really didn't know where to turn. And we use nutrition and LDN. 

I treat mostly men with Hashimoto.

I just recently got someone with renal failure. I put them on LDN and he's actually no longer headed for dialysis. He had told him he was going to pass away in the next year or two and he's actually doing very well. And I think LDN was a big part of that.

Regarding gut issues, 'll do a breath test for SIBO and H pylori. Those are best detected by a breath test and then still test them. Or I like to look for overgrowth of fungus, parasites, inflammatory markers, food allergies, that kind of thing. There are blood tests too for food allergies.

I feel like they're a little bit less accurate than the stool test, but I'll use a combo of those things to get to the bottom of the case and get it figured out. If necessary I also put them on an anti-inflammatory, gluten, dairy, and sugar-free diet. I called them kryptonite when I talked to my patients and I feel that they are inflammatory.

Our clinic is in North gate, which is in Seattle, just north of downtown. Our phone number is (206) 925-3525. And our website is www.seattleadvancedthyroid.com.

Summary of Dr Leslie DeGasparis interview. Watch the video for the full interview.

Leesa shares her Hyperthyroidism and LDN story - 7th March 2018 from LDN Research Trust on Vimeo

Leesa from the United States takes Low Dose Naltrexone (LDN) for Hypothyroidism and other conditions.

Doctors found my thyroid problems when I was 21. And I am now 36.

So I've been struggling with this for over a decade. I have Hypothyroidism, which is for low active thyroid. On top of the Hypothyroidism, I produced at autoimmune that we are trying to find out what was going on with the autoimmune and never could pinpoint the autoimmune through multiple different specialists and doctors that I continued to go.

My thyroid problems cause body aches, weight gain, hair loss, lack of sleep.

I would get on different medications, and it would make my thyroid go up into hyper. And then I would have the reverse where I could not sleep, lost weight. And so it was just kind of a yoyo effect going back and forth on. I produced  Epstein bar,

That makes me feel lethargic all the time. My serotonin levels are really bad. I'm trying to get up in the morning. The more tasks you have to do during the day they call it a fight or flight mechanism for not having the correct pituitary gland problems with your thyroid not being produced.
So your thyroid usually does not have a problem. It's something else in your body that reacts to that, and it attacks your thyroid.

I had a cyst and some mornings I'd wake up, and I wouldn't have a voice. And if my voice came back, it would be shallow. I would go to eat something, and I would get choked.

I would lay down and feel like I was being suffocated. In 2009, after I years, I ended up having the mass removed on the right side of my whole thyroid on the right side, which I still have just my left thyroid at this point.

So for the rest of my life has to be on the thyroid medicine to regulate my thyroid, since I just have one left side of my thyroid.

I started LDN in March of 2017.  So I've been on LDN for nine months.

Before that, everything that goes with that with the Epstein BARR, I had increased anxiety that I'd never had before. I would wake up, and I had nerve endings that were on the top of my skin. I just felt like I'd been in the freezer.

I had really bad leg cramps, Restless Leg Syndrome starting and they were looking at maybe some Rheumatoid Arthritis.

So in April started feeling a little bit better. Each month we're upping my dose of LDN by the 0.5 mg. I'm currently on 4.5 milligrams, and I've been on that for probably about three months now.
My thyroid is now regulated. I take a natural thyroid medication called WP thyroid. And this is the first time I've been on the same dose for six months now.

My levels always stayed in the middle of where your thyroid levels should be.
I would say my quality of life before LDN on most days I would say probably a two out of ten to where I was just struggling to get up every morning.

And the only reason I was doing that is because I had two kids that were relying on me all the time to be there for them.

Now I am walking jogging three miles. I work four days a week, then massage therapy.

I have at least six clients a day. I am constantly busy, and I'm able to work all day. Now my quality of life is a nine. I'm continuing every day to get better and work on getting better.
I've lost 58 pounds a little over a year. I think my kids are amazed to have their mum be able to do so many things with them where you couldn't before.

Leesa's summary interview. Please watch the video above for the full interview.

Dr Ted Cole - 3rd Jan 2018 from LDN Research Trust on Vimeo.

Dr Ted Cole shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Dr Ted Cole is an Integrative doctor and runs his “Cole Center of Healing” in Westchester, Ohio. He first utilised Low Dose Naltrexone (LDN) for hashimotos and thyroid problems, but quickly discovered it was invaluable for all types of autoimmune conditions. 

He treats a broad spectrum of diseases and does various methods of testing to evaluate the illness and monitor improvement. Dr Cole looks for vitamin and mineral deficiencies as well. 

Many of us are unaware we are lacking sufficient Vitamin D, magnesium, potassium, Vitamin C, and B complex. He wishes more doctors were aware of LDN for cancer and highlights LDN and it’s efficacy and safety.

This is a summary of Dr Ted Cole’s interview. Please listen to the rest of Dr Cole’s story by clicking on the video above.

Amy on the LDN Radio Show - 13th December 2017 (Low dose naltrexone) (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Amy from the United States shares her Sjögren's Syndrome and LDN Story on the LDN Radio Show with Linda Elsegood.

Amy first noticed an issue with her health when she began to have a constant pain in her pelvis. She initially attributed it to her running, but as other symptoms developed she went to a neurologist who was unable to diagnose her.

Determined to find the cause of her pain, she went to get blood tests at a local clinic who eventually diagnosed her Amy with Sjögren's Syndrome. Low Dose Naltrexone (LDN) has helped her to get over her ‘stiff person’s syndrome’ and get back to running regularly.

This is a summary of Amy’s interview. Please listen to the rest of Amy’s story by clicking on the video above.