LDN Video Interviews and Presentations

Dr Wai Liu, LDN Radio Show 2016 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr. Wai Liu is from St. George’s Hospital in London UK. He had just published a paper on how low dose naltrexone (LDN) can affect certain cancer cell lines in the laboratory that hopefully will drive clinical trials, then get approval for LDN as a treatment for cancer.

They took cells from patients with certain forms of cancer and compared the effects on the gene expression profiles by LDN, and conventional-dose naltrexone. Genes involved in cell cycling, the way cancer cells can grow, can be controlled in the way they proliferate. They showed LDN could target certain genes responsible for the cell cycle, and if that was exploited, they might get a handle on how cancer would grow. Indeed, they showed LDN does slow the growth of certain cancer cells via its effect on these particular proteins. As well, they found that because of the effects on the cell cycle, LDN increased the proteins that controlled the ability of a cell to undergo cell death, and increase cell killing in those cancer cells.

Furthermore, after administering LDN for a few days followed by no LDN for a recovery phase, they found continued cell killing, something bizarre to them, but similar to what happens with other drugs such as cannabinoids, or a couple other agents. In certain situations they saw LDN as having no effect on cancer cells, but during the recovery phase, there was a much improved level of cell killing.

They also used different schedules of chemotherapy alongside LDN, like gemcitabine, oxaliplatin, and something else like cyclophosphamide, as they are proven cytotoxic agents. They showed on a laboratory petri dish level, that when using both LDN and a number of cytotoxic agents, there was a much-increased level of proteins such as BAX, that regulate the ability of a cancer cell to undergo cell death. Understanding the profile of how drugs work lets you predict the best drugs to combine with the drug you’re testing. So for example, using a form of chemotherapy that requires BAX to be present and LDN results in cooperation between two different drugs.

Dr. Liu is not aware of doctors using this information clinically. There are many anecdotal reports of how LDN can help alleviate cancer symptoms or help with cancer treatment. More research is needed to show the benefits of LDN in cancer patients, and in combination with various chemotherapies or immunotherapies. LDN does things to cancer cells, and people are beginning to see the value in LDN. The more people hear and read about LDN, and with an increasing amount of scientific literature to support LDN as a cancer therapy, the better chance to attract funding for clinical trials.

Summary from Dr. Wai Liu, listen to the video for the show.

Keywords: LDN, low dose naltrexone, cancer, chemotherapy, immunotherapy

Any questions or comments you may have, please contact us. I look forward to hearing from you. 

Dr Tom O’Bryan, LDN Radio Show 12 July 2017 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr Tom O'Bryan shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Wheat sensitivity can cause an immune response, not just gluten. Hydrochloric acid in the stomach breaks down the proteins and enzymes in the gut convert them to amino acids, which permeate the intestines and enter the bloodstream. Wheat causes increased intestinal permeability ("leaky gut") in everyone, but not everyone suffers from eating wheat because wheat is a minor irritant. At some point, symptoms of intestinal permeability are likely to appear due to loss of oral tolerance, and can result in various autoimmune disorders, such as Hashimoto's. Reducing dietary wheat can arrest the development of autoimmune disorders. A wheat-free diet is easier to follow when patients understand that inflammation can be reduced by following the diet. His book, The Autoimmune Fix, has recipes. For example, take 1 Tbsp chia seeds, which are high in Omega 3s, stir into coconut milk till it starts to gel, refrigerate, add crushed fruit, and you get a healthy dessert.

Dr Tom O’Bryan, LDN Radio Show 27 Sept 2017 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr Tom O'Bryan shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Dr Tom O’Bryan discusses his book, The Autoimmune Fix. Expect continual OMGs.The prevalance of autoimmune disease is the #3 cause of getting sick and dying in the world. Autoimmune diseases progress over years, till enough tissue is damaged that enough symptoms appear to get a diagnosis. For example, a very early sign of Parkinson's is loss of sense of smell, and can be predictive of death within 5 years.

Measuring our antibodies can predict illness in its early stages. Antibodies cause cellular damage, then tissue damage, then inflammation, and eventually organ damage. 

Getting this in control early is important. Most of us are bombarded with toxins every day, so learning how to avoid them is crucial to a good healthy life. LDN is helpful in bolstering and regulating our immune system so that it can naturally fight off these elevated antibodies.

This interview includes some valuable knowledge for all listeners concerned with how to combat autoimmune diseases, cancers etc.

This is a summary of Dr Tom O’Bryan’s interview. Please listen to the rest of Dr O’Bryan’s story by clicking on the video above.

Dr Tom O’Bryan, LDN Radio Show 01 Feb 2017 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr Tom O’Bryan shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Dr Tom O’Bryan is the founder of www.thedoctor.com and is an internationally recognized speaker and workshop leader specializing in non-celiac gluten sensitivity and celiac disease. He hosted the gluten summit, and stars in the documentary series, betrayal, featuring the autoimmune solutions. He’s also written a book called ‘The Autoimmune Fix’.

In this interview Dr O’Bryan explains his many years of analysis in terms of the effect our diet can have upon our immune systems and subsequent immune responses we have to autoimmune diseases. The over-consumption of products such as milk, wheat and dairy in general can be damaging and our diets must be moderated.

This is a summary of Dr Tom O’Bryan’s interview. Please listen to the rest of Dr O’Bryan’s story by clicking on the video above.

Dr Thomas Cowan, LDN Radio Show 14 Dec 2016 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr Thomas Cowan shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Dr Thomas Cowan practices holistic medicine in San Francisco and prescribes Low Dose Naltrexone (LDN). He also has a new book called ‘Human Heart, Cosmic Heart’.

He first heard of LDN in 1992 from one of his patients with AIDS who requested it. This occurred again four years later, prompting Dr Cowan into researching LDN more thoroughly and learning about its many benefits in combating autoimmune diseases.

He says that LDN’s side effects are very uncommon and that in 95% of his autoimmune patients, he has prescribed LDN. Dr Cowan is a strong advocate of LDN.

This is a summary of Dr Thomas Cowan’s interview. Please listen to the rest of Dr Cowan’s interview by clicking on the video above.

Dr Thomas Cowan, LDN Radio Show (LDN, low dose naltrexone) from LDN Research Trust on Vimeo

Dr Thomas Cowan shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Dr Thomas Cowan first came across Low Dose Naltrexone (LDN) around 20 years ago when one of his close friends had incurable lymphoma. Having refused to continue on conventional treatment which had little to no effect on improving his health, he researched alternative treatments and came across LDN which drastically helped him to recover.

In the last decade of his career, Dr Cowan has predominantly treated patients with Ulcerative Colitis (UC) and Crohn’s Disease, finding that LDN can be successful in treating both diseases and providing great relief to his patients.

This is a summary of Dr Thomas Cowan’s interview. Please listen to the rest of Dr Cowan’s story by clicking on the video above.

Dr Steven Richeimer, LDN Radio Show (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr Steven Richeimer shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Dr Steven Richeimer primarily uses Low Dose Naltrexone (LDN) for neuropathic pain diagnosis, including fibromyalgia which closely relates to complex regional pain syndrome.

In this interview he stresses the importance of the patient researching LDN thoroughly, particularly if it's compatible with any current medication you may be taking. Nevertheless, LDN is highly compatible with a number of treatments and can often compliment your current plan and improve its benefits on your health.

Dr Richeimer mentions that often the longer a patient is off their opioids, the more likely the patient is to see the benefits of LDN.

This is a summary of Dr Steven Richeimer’s interview. Please listen to the rest of Dr Richeimer’s story by clicking on the video above.

Pharmacist Skip Lenz, LDN Radio Show 27 Nov 2019 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Pharmacist Dr. Skip Lenz from United States talks about his experience prescribing Low Dose Naltrexone.

Approximately in December of 1999, I had a patient who was on another product for Multiple Sclerosis who asked me to walk into this new thing, Naltrexone low dose.

There was a doctor up in New York who was prescribing it and was getting tremendous results with MS Patients. So I looked into it and I had several conversations with dr. Bahari, who was a clinical innovator of the year. And the rest literally is history.

We're now always down 100 to 200 scripts at the end of the week.

Back in 1999 we did a clinical study to close to a thousand MS patients and 83% not had an exacerbation in greater than three years.

I started taking LDN for Rheumatoid Arthritis about six years ago for prophylaxis. I'm a pharmacist. I have access to literally anything, nothing worked very well.  After three months, four months after I started my LDN, I wasn't taking Ibuprofen anymore.

LDN still hasn't been FDA approved. I was skeptical the first year. This is one of the reasons why I did our survey. Is working so therefore that's the reason why I am an advocate of it.

I've been a pharmacist since 1973. First of all, I have a conversation with my patients about what they're doing and what have they tried, what are their symptoms, what are their expectations of LDN. It's again, my experience that sometimes in a niche stuation, whatever the disease is in an acute situation, you may or may not get the result that you expect in a chronic situation and you're generally going to judge the expected result.

My experience it's either going to work somewhat in six months or it's not going to work at all. What I mean by somewhat is that you might only be getting, 20, 30, 40% of the results that you are expecting in six months, that you should be getting some sort of results.

Summary from Dr. Skip Lenz's interview. Listen to the video for the full interview.

Nurse Practitioner Seth Merritt, LDN Radio Show (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Seth Merrit, LMT, FNP, CATOM, CLS

shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Seth Merritt is a nurse practitioner from Portland, Oregon who prescribes Low Dose Naltrexone (LDN). He himself takes LDN for psoriasis and has a great deal of success.

Having witnessed his own recovery on LDN, he was determined to ensure that others do not miss out on the opportunity to try the drug. 

In this interview he explains how he finds LDN to be very successful in treating many of his patients with fibromyalgia.

This is a summary of Seth Merritt’s interview. Please listen to the rest of Seth’s story by clicking on the video above.

Dr Scott Zashin, LDN Radio Show 2017 (LDN, low dose naltrexone) from LDN Research Trust on Vimeo.

Dr Scott Zashin shares his Low Dose Naltrexone (LDN) experience on the LDN Radio Show with Linda Elsegood.

Doctor Zashin from Dallas, Texas, is a Rheumatologist who is Board Certified in Internal Medicine. 20 years ago he changed his practice to specialize in autoimmune conditions which required more time to evaluate and treat. 

Unlike most Doctors who allow only 10 to 15 minutes per visit, he spends an hour or more as necessary to get a firm grasp of the patient's problems. He discusses the many autoimmune conditions he treats and how LDN fits in, and why diet and exercise are very important.

This is a summary of Dr Scott Zashin’s interview. Please listen to the rest of Dr Zashin’s story by clicking on the video above.