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Low Dose Naltrexone (LDN) and itching
LDN when first starting can have some side effects albeit rare. Some more common ones include sleep disturbance and vivid dreams. Some lesser ones can include rashes, nausea, irritability. In very rare cases it can cause an increase in the symptoms that it is taken for. Discontinuation rates are rather low, around 1 to 5% in my clinical experience. Skin itching is in theory one of the side-effects but again very rare. One should exclude other reasons (compounding pharmacies may use fillers and those substances may be the cause of the itching); so before you call it a ''fail'' have a very clean compounded LDN prescription void of any synthetics, food coloring, gluten and dairy products. Incidentally, naltrexone can be used to treat severe and intractable pruritus (itching) associated with cholestatic patients and those suffering from other conditions.