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Low-Dose Naltrexone: A New Therapy Option for Complex Regional Pain Syndrome Type I Patients
Int J Pharm Compd
May-June 2016
https://www.ncbi.nlm.nih.gov/pubmed/28333660
Naltrexone (an opioid antagonist) has long been used in patients overcoming alcohol and opioid dependency. However, at doses one-tenth of those commonly prescribed for the above conditions, an unexpected effect occurs that aids in alleviating pain. Although there are currently no randomized clinical trials supporting the use of low-dose naltrexone, we present a case study describing the impact of compounding low-dose naltrexone that has dramatically improved the patient's pain symptoms which were refractory to other treatments.