Low Dose Naltrexone Reduces In Vitro Endoplasmic Reticulum Stress and Stimulates Wound Healing in Intestinal Epithelial Cells (Abstract)

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Low Dose Naltrexone Reduces In Vitro Endoplasmic Reticulum Stress and Stimulates Wound Healing in Intestinal Epithelial Cells

Journal of Crohn's and Colitis
March 2016
https://academic.oup.com/ecco-jcc/article/10/suppl_1/S136/2481649

Naltrexone (NTX), a μ-opioid receptor (MOR) antagonist, up regulates MOR and its ligands when used at low doses. It may have a beneficial effect in the treatment of IBD by directly stiumulating epithelial wound healing and reducing intestinal ER stress.