Is Melatonin Safe For People with Autoimmune Conditions?

Is melatonin safe for people who have autoimmune conditions? Generally the answer is yes but much like vitamin D, Naltrexone or any other thing we talked about today sometimes if you have melatonin going in and you have autoimmunity that's unchecked and uncontrolled you get an immunomodulator that is is also going into an uncontrolled system. 

If I were to roll up a newspaper and throw it over on the floor nothing would happen with it other than it would clutter up my floor.  On the other hand I have a fireplace over here that's lit and there's a fire in it. I crumple that up and I roll it over there and it goes in the fireplace. It becomes a fuel source for the fire. The fire gets bigger. A lot of immunomodulatory substances and a lot of other things that are more stimulating are like that ball of rolled up newspaper.  If there's no fire around you can roll them all over the place and they just clutter things up or do whatever they're going to do.  If there's inflammation the fire is burning we have to calm the fire down or get it under control before we start throwing things that are substrate for things that aregoing to feed it.  

Yes it's safe but just like Naltrexone or other stuff melatonin into an unregulated system can feel like it's not helping or it's aggravating because the rest of the system needs to be calmed down.