Micro dosing of Low Dose Naltrexone LDN

I'm almost up to 0.25 milligram. I got three viruses about two months after I started. One was Covid. Was that just coincidence or did it lower my immune system?

Michelle Moser: No, it's quite the opposite.

I'm also taking it for histamine. Intolerance reactions such as dizziness, IBS, inflammatory responses. It seems when I raised my dose I got a darn virus. Right now I'm taking about a third of a .25 milligram.

Michelle Moser: I don't know how you take a third of a 0.25 milligram capsule. I really hope you're not opening that up and trying to dissect that. That's not accurate . Ask about liquids, or ask about a smaller dose to be much more effective. I don't know how you're going to chase 0.25 milligrams in a capsule, even a tablet, especially a capsule whose volume could be 130 milligrams. I just don't know how that would work. So I think that there could be some dosing issue here. It could very well be that if you are dividing your dose, you're literally not taking Low Dose Naltrexone (LDN) for quite some time, and that may be leaving your immune system open and susceptible.

But low dose naltrexone, we know, helps to modulate the immune system. It works on very specific pathways, and if anything, we have seen that those individuals who have been on low dose naltrexone have a lower incidence of COVID infection and reaction. At least in the United Sates, there are several studies going on about using low dose naltrexone (LDN) for COVID, and the potential for infection duration as well as severity. So there's a wide variety of arms to those studies that are happening.

Starting October 2019, this is the first year, and you've been out and about since 2019. I think what needs to happen in this situation is because of IBS and because of the inflammatory responses, I think it may be a good idea to find a different dosage form of low dose naltrexone and again start at 0.25 milligrams, or even 0.1 milligram, and then slowly increase from there. Perhaps your increase-interval isn't every 7 days. Perhaps it needs to be a little bit longer, and then working from there.

I just think that low dose naltrexone is incredibly helpful for histamine intolerance. Moving that TH1 to TH2, that's where you're going to decrease the dizziness because of how it actually works in the ears with the cochlea, and perhaps your immune system is just not seeing the benefits of LDN because of breaking the dose up

Answered by Michelle Moser, RPh, FACA, FACVP
LDN Specialist

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