With regards to Hashimoto’s do you expect the Low Dose Naltrexone (LDN) dose to reach 4.5 or stay lower permanently?
So in Hashimoto's disease, we spoke about patients needing a smaller dose sometimes or a slower initiation so that they can get the best benefit without any side effects.
Hashimoto's disease is a disease of the thyroid gland, where there's autoimmune activity against the thyroid gland. In some people, when you take LDN, that autoimmunity seems to reverse very quickly, and the thyroid gland comes back on and starts producing lots of thyroid hormones again.
However, these patients are also taking oral supplementation of thyroid hormones. So, when your thyroid gland starts working again and you're also taking the oral supplementation of thyroid hormones, you can get this incredible buildup of thyroid hormones, and it happens very quickly.That can cause some serious side effects.
With Hashimoto's, we do like low and slow, gently does it. Test your thyroid gland as you go, but the final dose that you get to is symptom-dependent or results-dependent. So, most people do get to 4.5, it just takes a bit longer.