Thyroids, chemicals and cabbage: Have we been worrying about the wrong thing?
Another recent study shows how thyroid autoimmunity can be caused by common environmental pollutants such as BPA, flame retardant chemicals and formaldehyde. The gist is that chemicals can bind to proteins in the bloodstream, causing them to change into a new shape that the immune system may recognize as an antigen to attack. In some unlucky people, the molecular shape of the antigen is very similar to that of some thyroid tissue or thyroid hormone. So the antibodies created to attack one will also attack the other. It’s a case of mistaken identity between molecules that look too much alike.
The article is linked.
As someone with an autoimmune condition of the thyroid, I take these two studies to suggest I should be less concerned about cabbage and more concerned about chemicals.
Petroski W, Minich DM. Is There Such a Thing as "Anti-Nutrients"? A Narrative Review of Perceived Problematic Plant Compounds. Nutrients. 2020;12(10):E2929. Published 2020 Sep 24. doi:10.3390/nu12102929
Kharrazian D, Herbert M, Vojdani A. Cross-Reactivity between Chemical Antibodies Formed to Serum Proteins and Thyroid Axis Target Sites. Int J Mol Sci. 2020;21(19):E7324. Published 2020 Oct 3. doi:10.3390/ijms21197324
Link to Article