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In Response Comments on "Low-Dose Naltrexone Use for Patients with Chronic Regional Pain Syndrome: A Systematic Literature Review"
Pain Physician
December 2021
https://www.painphysicianjournal.com/current/pdf?article=NzM4NQ%3D%3D
The authors of “Low-Dose Naltrexone Use for Patients With Chronic Regional Pain Syndrome,” conducted a systematic literature review to determine the effects of low-dose naltrexone (LDN) in the treatment of chronic pain disorders, with an emphasis on complex regional pain syndrome (CRPS). They believe the lack of relevant studies serves as an important call for additional research into the safety and efficacy of LDN for CRPS and other chronic pain syndromes.