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Restless Leg Syndrome - Leonard Weinstock, MD (2021 Conference) (LDN, low dose naltrexone)
This lecture starts with the known and newer pathophysiology to try to uncover new ways of treating restless legs syndrome (RLS). Using case studies, he links RLS with small intestinal bacterial overgrowth (SIBO), low iron, and other autoimmune disorders. Treatment examples are provided
LDN could increase endorphin levels in the brain, possibly protecting against low iron levels and dopamine dysfunction. It can increase motility and migrating motor complex in the gut, allowing for the gut to work better after antibiotic therapy, and thus reduce the recurrence of SIBO. Its action as a toll-receptor blocker reduces pain and helps RLS patients. GI symptoms and SIBO are common in RLS. If you determine somebody has CBOE and you are very aggressive in treating that with antibiotics, diet, motility therapy, and gut protection and anti-inflammatory reaction therapy, probiotics, zinc and LDN and you're attentive to their iron level and vitamin D levels, you'll find success in your patients.
KEYWORDS: restless legs syndrome (RLS), iron deficiency, inflammation, LDN, endorphin, SIBO, celiac, fibromyalgia, Crohn's, IBS, mast cell activation syndrome (MCAS), HIV
This is a summary of the presentation. Watch the video for full information.