Is Sublingual Low Dose Naltrexone (LDN) the Best Form to Take?

LDN Specialist Pharmacist Michelle Moser
LDN Specialist Pharmacist Michelle Moser

 

Is Sublingual Low Dose Naltrexone (LDN) the Best Form to Take?

The question was asked: is sublingual LDN the best form to take? The answer depends on who is taking it.  Sublingual means it's absorbed underneath the tongue or inside the cheek cavity.  Not all LDN when placed underneath the tongue or in the cheek cavity is absorbed 100 percent.

Sublingual a lot of times it becomes oral as well. There are people with autoimmune disease or gastrointestinal issues (such as Crohn's disease or ulcerative colitis) that  have issues absorbing.  Some people with Hashimoto thyroiditis for example usually there's some absorption issues.  So using a sublingual form might be better for that individual but it might not necessarily be the best route for everybody. 

Also, oral capsules or tablets might not be the best form for everybody.  Many autistic peope do not take oral medications at all.  In that case they can use transdermal LDN, that goes all the way through the skin into the capillary beds or into the large vein system and we put that transdermal LDN on very specific sites on the body.  We know that the blood supply is great and we know that it's going to be delivered.  

Transdermal LDN has a 2.64 hour delay in absorption so that needs to be taken into account.  Also, a sublingual is helpful in using very low dose or microgram dosing.  The best form is what's working for you.