Timing to take Low Dose Naltrexone (LDN)

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LDN Specialist Pharmacist Michelle Moser
LDN Specialist Pharmacist Michelle Moser

Timing of Low Dose Naltrexone (LDN)

This lovely lady comes in and she says her cortisol peaks around 4 pm, low normal 8 am. How to find out if my endorphin timing is also mucked? How, or would they, then peak at 2 am? Trying to figure out when to take LDN. I think LDN dosed at bedtime is always going to be the best place to start. I would start low and go slow, however whatever that dosing is, whether you start at .5, 1.5, 1.0, 1.5, it again depends on that individual and exactly what are you using LDN for. Just because your cortisol is on this roller coaster ride, that may not be the real reason why you're taking LDN. There's obviously a lot of other things going on, so start low, go slow, find where your happy dose is, like Steven had in the previous question. Sometimes you bump it up a dose and you don't feel as good as you did on a lower dose, so less is more. So I that's what I would do, is to figure that out now how LDN actually works with the HPA axis, and how it actually works in the brain with those chemicals. You're always going to have an increase in endorphins and because it does, it will block those receptors which will cause you to make your own endorphins. But that is different than cortisol so I'm a little confused. I think we need more information on this question