The Uses of Low-Dose Naltrexone in Clinical Practice
BMJ Case Reports
The purpose of this paper is to review low-dose naltrexone (LDN) for use in clinical practice. The known or theoretical mechanism of action of LDN, clinical research findings in relation to various medical conditions including pain, autoimmune conditions, cancer, and mood disorders will be discussed. Recommended doses and forms of LDN will also be summarized.
Keywords: low-dose naltrexone, LDN, clinical research, ENDO1639A, OGF/OGFr axis, autoimmune conditions, rheumatoid arthritis, Crohn’s disease, multiple sclerosis, post traumatic stress syndrome
Keywords by Erin Williams, student, St. Louis College of Pharmacy